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Mezlocillin and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with mezlocillin.

Moderate

Mezlocillin High Blood Pressure (Hypertension)

Moderate Potential Hazard, High plausibility

mezlocillin - sodium/potassium

Parenteral mezlocillin sodium contains approximately 43 mg (1.85 mEq) of sodium per each gram of mezlocillin activity. The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention. In addition, hypokalemia has been reported rarely during therapy with mezlocillin and other extended-spectrum penicillin antibiotics, which may be particularly important to bear in mind when treating patients with low potassium reserves or fluid and electrolyte imbalance. Clinical monitoring of electrolytes is recommended if these agents are used for prolonged periods.

References

  1. Parry MF, Neu HC (1982) "The safety and tolerance of mezlocillin." J Antimicrob Chemother, 9, p. 1-8
  2. Nanji AA, Lindsay J (1982) "Ticarcillin associated hypokalemia." Clin Biochem, 15, p. 118-9
  3. (2002) "Product Information. Mezlin (mezlocillin)." Bayer

Mezlocillin drug interactions

There are 41 drug interactions with mezlocillin.

Mezlocillin disease interactions

There are 5 disease interactions with mezlocillin which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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