Tranxene T-Tab and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with Tranxene T-Tab (clorazepate).
Clorazepate Food
Moderate Food Interaction
Alcohol can increase the nervous system side effects of clorazepate such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with clorazepate. Do not use more than the recommended dose of clorazepate, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
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Clorazepate Obesity
Moderate Potential Hazard, Moderate plausibility
benzodiazepines - obesity
The plasma half-lives of benzodiazepines may be prolonged in obese patients, presumably due to increased distribution into fat. Marked increases in distribution (> 100%) have been reported for diazepam and midazolam, and moderate increases (25% to 100%) for alprazolam, lorazepam, and oxazepam. Therapy with benzodiazepines should be administered cautiously in obese patients, with careful monitoring of CNS status. Longer dosing intervals may be appropriate. When dosing by weight, loading doses should be based on actual body weight, while maintenance dose should be based on ideal body weight to avoid toxicity.
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Tranxene T-Tab drug interactions
There are 505 drug interactions with Tranxene T-Tab (clorazepate).
Tranxene T-Tab disease interactions
There are 10 disease interactions with Tranxene T-Tab (clorazepate) which include:
- acute alcohol intoxication
- closed-angle glaucoma
- drug dependence
- psychosis
- renal/liver disease
- respiratory depression
- seizures
- depression
- obesity
- paradoxical reactions
More about Tranxene T-Tab (clorazepate)
- Tranxene T-Tab consumer information
- Check interactions
- Compare alternatives
- Reviews (3)
- Drug images
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: benzodiazepines
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.