Spectracef and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Spectracef (cefditoren).
Cefditoren Food/Lifestyle
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food enhances the oral absorption and bioavailability of cefditoren pivoxil. According to the manufacturer, administration of cefditoren pivoxil following a high-fat meal increased the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by 50% and 70%, respectively, compared to administration in the fasting state. The absolute bioavailability of cefditoren pivoxil is approximately 14% under fasting conditions and 16% when given with a low-fat meal.
MANAGEMENT: To ensure maximal oral absorption, cefditoren pivoxil should be administered with or immediately after a meal.
References (1)
- (2001) "Product Information. Spectracef (cefditoren)." TAP Pharmaceuticals Inc
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Spectracef drug interactions
There are 69 drug interactions with Spectracef (cefditoren).
Spectracef disease interactions
There are 6 disease interactions with Spectracef (cefditoren) which include:
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- During pregnancy
- Drug class: third generation cephalosporins
- Breastfeeding
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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