Acetaminophen/aspirin and Alcohol/Food Interactions
There are 3 alcohol/food/lifestyle interactions with acetaminophen / aspirin.
Aspirin Caffeine
Minor Drug Interaction
Information for this minor interaction is available on the professional version.
Acetaminophen Alcohol (Ethanol)
Major Drug Interaction
Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Aspirin Alcohol (Ethanol)
Moderate Drug Interaction
Ask your doctor before using aspirin together with ethanol. Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Acetaminophen/aspirin drug interactions
There are 450 drug interactions with acetaminophen / aspirin.
Acetaminophen/aspirin disease interactions
There are 12 disease interactions with acetaminophen / aspirin which include:
- alcoholism
- liver disease
- coagulation
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- PKU
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
More about acetaminophen / aspirin
- acetaminophen/aspirin consumer information
- Check interactions
- Compare alternatives
- Reviews (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: analgesic combinations
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.