Xeljanz Drug Interactions
Currently displaying a list of 670 drugs known to interact with Xeljanz (tofacitinib).
- 377 major drug interactions
- 282 moderate drug interactions
- 11 minor drug interactions
Medications known to interact with Xeljanz
Note: Showing generic names only.
A
- abametapir topical
- abatacept
- abemaciclib
- abrocitinib
- acalabrutinib
- acebutolol
- adagrasib
- adalimumab
- adenovirus vaccine
- afamitresgene autoleucel
- aldesleukin
- alefacept
- alemtuzumab
- alfentanil
- allogeneic processed thymus tissue
- altretamine
- aminoglutethimide
- amiodarone
- amobarbital
- amprenavir
- anakinra
- anifrolumab
- anthrax vaccine adsorbed
- anti-thymocyte globulin (rabbit)
- apalutamide
- aprepitant
- armodafinil
- asciminib
- ashwaganda
- asparaginase escherichia coli
- aspirin
- atazanavir
- atenolol
- atezolizumab
- avacopan
- avapritinib
- avelumab
- axicabtagene ciloleucel
- azacitidine
- azathioprine
B
- baricitinib
- basiliximab
- bcg
- bcg vaccine
- belantamab mafodotin
- belatacept
- belimumab
- belinostat
- belzutifan
- bendamustine
- benralizumab
- benzgalantamine
- bepridil
- berotralstat
- betamethasone
- betaxolol
- bexarotene
- bifidobacterium infantis
- bifidobacterium longum
- bimekizumab
- bisoprolol
- bleomycin
- blinatumomab
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brentuximab
- bretylium
- brewer's yeast
- brexucabtagene autoleucel
- brigatinib
- brodalumab
- bromfenac
- budesonide
- buprenorphine
- busulfan
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- canakinumab
- candida albicans extract
- capecitabine
- capivasertib
- carbamazepine
- carboplatin
- carfilzomib
- carmustine
- carteolol
- carvedilol
- cat's claw
- celecoxib
- cemiplimab
- cenobamate
- ceritinib
- certolizumab
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chlorambucil
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- chlorotrianisene
- cholera vaccine
- cholera vaccine, live
- choline salicylate
- ciltacabtagene autoleucel
- ciprofloxacin
- cisplatin
- cladribine
- clarithromycin
- clofarabine
- clomiphene
- clonidine
- clozapine
- cobicistat
- cobimetinib
- coccidioidin skin test
- codeine
- conivaptan
- conjugated estrogens
- conjugated estrogens topical
- copanlisib
- corticorelin
- corticotropin
- cortisone
- cosibelimab
- cosyntropin
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- crizotinib
- crovalimab
- cyclophosphamide
- cyclosporine
- cytarabine
D
- dabrafenib
- dacarbazine
- daclizumab
- dactinomycin
- danicopan
- daprodustat
- daratumumab
- daridorexant
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- decitabine
- deferasirox
- deferiprone
- deflazacort
- dehydroepiandrosterone
- delavirdine
- dengue vaccine
- denileukin diftitox
- denosumab
- deucravacitinib
- dexamethasone
- dezocine
- diclofenac
- dienestrol topical
- diethylstilbestrol
- diflunisal
- digitoxin
- digoxin
- diltiazem
- dimethyl fumarate
- dinutuximab
- diroximel fumarate
- disopyramide
- docetaxel
- dofetilide
- donepezil
- dostarlimab
- doxorubicin
- doxorubicin liposomal
- dronedarone
- drospirenone
- dupilumab
- durvalumab
- duvelisib
E
- echinacea
- eculizumab
- efalizumab
- efavirenz
- efgartigimod alfa
- eflornithine
- elagolix
- elderberry
- elotuzumab
- elranatamab
- encorafenib
- enfortumab vedotin
- enzalutamide
- epcoritamab
- epirubicin
- eribulin
- erlotinib
- erythromycin
- eslicarbazepine
- esmolol
- esomeprazole
- esterified estrogens
- estradiol
- estradiol topical
- estramustine
- estrone
- estropipate
- estropipate topical
- etanercept
- ethinyl estradiol
- etodolac
- etonogestrel
- etoposide
- etrasimod
- etravirine
- everolimus
F
- fam-trastuzumab deruxtecan
- fedratinib
- felbamate
- fenfluramine
- fenoprofen
- fentanyl
- fexinidazole
- fingolimod
- flecainide
- floxuridine
- fluconazole
- fludarabine
- fludrocortisone
- fluorouracil
- flurbiprofen
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- fruquintinib
G
- galantamine
- ganciclovir
- gemcitabine
- gemtuzumab
- givinostat
- glofitamab
- golimumab
- griseofulvin
- guanabenz
- guanfacine
- guselkumab
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- human papillomavirus vaccine
- hydrocodone
- hydrocortisone
- hydromorphone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyurea
I
- ibritumomab
- ibrutinib
- ibuprofen
- ibutilide
- idarubicin
- idecabtagene vicleucel
- idelalisib
- ifosfamide
- imatinib
- imetelstat
- inavolisib
- indinavir
- indomethacin
- inebilizumab
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- inotuzumab ozogamicin
- interferon alfa-2a
- interferon alfa-2b
- interferon alfa-n1
- interferon alfacon-1
- interferon gamma-1b
- iobenguane I 131
- iodine i 131 tositumomab
- ipilimumab
- iptacopan
- irinotecan
- irinotecan liposomal
- isatuximab
- isavuconazonium
- itraconazole
- ivosidenib
- ixabepilone
- ixazomib
- ixekizumab
J
K
L
- labetalol
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- landiolol
- lansoprazole
- larotrectinib
- lazertinib
- lefamulin
- leflunomide
- lenacapavir
- lenalidomide
- letermovir
- levamisole
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- levorphanol
- lidocaine
- lifileucel
- linezolid
- lisocabtagene maraleucel
- lofexidine
- lomustine
- lonafarnib
- lonapegsomatropin
- loncastuximab tesirine
- lorlatinib
- lurbinectedin
- lutetium lu 177 dotatate
- lutetium lu 177 vipivotide tetraxetan
- lyme disease vaccine
- lymphocyte immune globulin, anti-thy (equine)
M
- magnesium salicylate
- mavacamten
- mavorixafor
- measles virus vaccine
- mechlorethamine
- meclofenamate
- medroxyprogesterone
- mefenamic acid
- megestrol
- meloxicam
- melphalan
- melphalan flufenamide
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- meperidine
- mephobarbital
- mepolizumab
- mercaptopurine
- methadone
- methotrexate
- methyldopa
- methylprednisolone
- metoprolol
- mexiletine
- mibefradil
- miconazole
- midostaurin
- mifepristone
- mirikizumab
- mitapivat
- mitomycin
- mitotane
- mitoxantrone
- mixed respiratory vaccine
- mobocertinib
- modafinil
- mogamulizumab
- momelotinib
- monomethyl fumarate
- moricizine
- morphine
- morphine liposomal
- mosunetuzumab
- mumps skin test antigen
- mumps virus vaccine
- muromonab-cd3
- mycophenolate mofetil
- mycophenolic acid
N
- nabumetone
- nadofaragene firadenovec
- nadolol
- nafcillin
- nalbuphine
- naproxen
- natalizumab
- naxitamab
- nebivolol
- nefazodone
- nelarabine
- nelfinavir
- nevirapine
- nilotinib
- niraparib
- nivolumab
- norethindrone
- norgestrel
O
- obecabtagene autoleucel
- obinutuzumab
- ocrelizumab
- ofatumumab
- olaparib
- olaratumab
- oliceridine
- olutasidenib
- omacetaxine
- omaveloxolone
- omeprazole
- opium
- oritavancin
- osilodrostat
- osimertinib
- ospemifene
- oxaliplatin
- oxaprozin
- oxcarbazepine
- oxycodone
- oxymorphone
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- panobinostat
- pazopanib
- pegaspargase
- pegcetacoplan
- peginterferon alfa-2a
- peginterferon alfa-2b
- pembrolizumab
- pemetrexed
- penbutolol
- pentazocine
- pentobarbital
- pentostatin
- pertussis, acellular
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pindolol
- piroxicam
- pirtobrutinib
- plague vaccine
- plicamycin
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- polatuzumab vedotin
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- pomalidomide
- ponatinib
- ponesimod
- posaconazole
- pozelimab
- pralatrexate
- pralsetinib
- prednisolone
- prednisone
- primidone
- procainamide
- procarbazine
- progesterone
- progesterone topical
- promazine
- propafenone
- propoxyphene
- propranolol
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- radium 223 dichloride
- raloxifene
- ravulizumab
- remdesivir
- remifentanil
- repotrectinib
- reslizumab
- retifanlimab
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- risankizumab
- ritlecitinib
- ritonavir
- rituximab
- rivastigmine
- rofecoxib
- roflumilast
- romidepsin
- ropeginterferon alfa-2b
- rotavirus vaccine
- rozanolixizumab
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- saccharomyces boulardii lyo
- sacituzumab govitecan
- salsalate
- samarium sm 153 lexidronam
- saquinavir
- sarilumab
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- satralizumab
- secobarbital
- secukinumab
- selinexor
- selpercatinib
- siltuximab
- siponimod
- sipuleucel-T
- sirolimus
- sirolimus protein-bound
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- sodium phosphate p32
- sodium salicylate
- sodium thiosalicylate
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotalol
- sotorasib
- spesolimab
- st. john's wort
- staphage lysate (spl)
- stiripentol
- streptococcus salivarius
- streptozocin
- strontium-89 chloride
- sufentanil
- sulfinpyrazone
- sulindac
- sutimlimab
- suzetrigine
T
- tacrine
- tacrolimus
- tafasitamab
- talazoparib
- talimogene laherparepvec
- talquetamab
- tamoxifen
- tapentadol
- tarlatamab
- tazemetostat
- teclistamab
- tecovirimat
- telaprevir
- telithromycin
- telotristat
- temozolomide
- temsirolimus
- teniposide
- teplizumab
- teriflunomide
- tetanus toxoid
- thalidomide
- thioguanine
- thiotepa
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tildrakizumab
- timolol
- tisagenlecleucel
- tislelizumab
- tisotumab vedotin
- tocainide
- tocilizumab
- tolmetin
- topotecan
- toremifene
- toripalimab
- tositumomab
- trabectedin
- tramadol
- trastuzumab
- tremelimumab
- treosulfan
- triamcinolone
- triamcinolone ophthalmic
- trichophyton skin test
- trimetrexate
- trofinetide
- troglitazone
- troleandomycin
- tuberculin purified protein derivative
- tucatinib
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- vadadustat
- valdecoxib
- valganciclovir
- vamorolone
- varicella virus vaccine
- vedolizumab
- vemurafenib
- venetoclax
- verapamil
- vilobelimab
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vitamin e
- voclosporin
- vorasidenib
- voriconazole
- voxelotor
Y
Z
- zanubrutinib
- zidovudine
- zilucoplan
- zinc acetate
- zinc chloride
- zinc gluconate
- zinc sulfate
- ziv-aflibercept
- zolbetuximab
- zoster vaccine live
- zoster vaccine, recombinant
Xeljanz alcohol/food interactions
There are 2 alcohol/food interactions with Xeljanz (tofacitinib).
Xeljanz disease interactions
There are 13 disease interactions with Xeljanz (tofacitinib) which include:
- cardiovascular risk
- malignancy
- thrombosis
- infections
- tuberculosis
- viral reactivation
- cytopenias
- diabetes
- GI obstruction
- GI perforation
- hepatic disorder
- hyperlipidemia
- renal disease
Report options
QR code containing a link to this page
More about Xeljanz (tofacitinib)
- Xeljanz consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (145)
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- FDA approval history
- Drug class: antirheumatics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Rinvoq
Rinvoq (upadacitinib) is used to treat rheumatoid arthritis, psoriatic arthritis, atopic ...
Reviews & ratings
Entyvio
Entyvio (vedolizumab) is used to treat ulcerative colitis (UC) and Crohn's disease, reducing ...
Reviews & ratings
Otezla
Otezla (apremilast) is used to treat plaque psoriasis, psoriatic arthritis, and oral ulcers ...
Reviews & ratings
Skyrizi
Skyrizi (risankizumab) is used to treat plaque psoriasis, psoriatic arthritis, ulcerative colitis ...
Reviews & ratings
Omvoh
Omvoh is used to treat moderate to severe ulcerative colitis or Crohn's disease in adults. This ...
Reviews & ratings
Stelara
Stelara (ustekinumab) is used to treat Crohn's disease, ulcerative colitis, plaque psoriasis, and ...
Reviews & ratings
Taltz
Taltz (ixekizumab) is used to treat plaque psoriasis, psoriatic arthritis, and ankylosing ...
Reviews & ratings
Hydroxychloroquine
Hydroxychloroquine is a quinoline drug used to treat or prevent malaria. It's also used to treat ...
Reviews & ratings
Celecoxib
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation ...
Reviews & ratings
Dexamethasone
Dexamethasone is used to treat inflammatory conditions such as allergies, skin conditions ...
Reviews & ratings
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
