Robitussin-AC Interactions
There are 524 drugs known to interact with Robitussin-AC (codeine / guaifenesin), along with 16 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 125 are major, 396 are moderate, and 3 are minor.
- View all 524 medications that may interact with Robitussin-AC
- View Robitussin-AC alcohol/food interactions (1)
- View Robitussin-AC disease interactions (16)
Most frequently checked interactions
View interaction reports for Robitussin-AC (codeine / guaifenesin) and the medicines listed below.
- acetaminophen
- albuterol
- amlodipine
- aspirin
- atorvastatin
- benzonatate
- Colace (docusate)
- Flonase (fluticasone nasal)
- gabapentin
- ibuprofen
- Lantus (insulin glargine)
- Lasix (furosemide)
- levothyroxine
- Lipitor (atorvastatin)
- lisinopril
- losartan
- metformin
- metoprolol
- MiraLAX (polyethylene glycol 3350)
- multivitamin
- omeprazole
- prednisone
- Seroquel (quetiapine)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin D3 (cholecalciferol)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Robitussin-AC alcohol/food interactions
There is 1 alcohol/food interaction with Robitussin-AC (codeine / guaifenesin).
Robitussin-AC disease interactions
There are 16 disease interactions with Robitussin-AC (codeine / guaifenesin) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
Report options
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More about Robitussin-AC (codeine / guaifenesin)
- Compare alternatives
- Reviews (16)
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.