Generic name: LIDOCAINE 36mg
Dosage form: patch
Medically reviewed by Drugs.com. Last updated on Nov 14, 2018.
Important Dosage and Administration Instructions
Because of the difference in bioavailability of ZTLIDO compared to Lidoderm (lidocaine patch 5%), a different dosage strength is required to be administered to the patient. One ZTLIDO (lidocaine topical system) 1.8% provides equivalent lidocaine exposure to one Lidoderm (lidocaine patch 5%) [see Clinical Pharmacology ( 12.3)] .
When ZTLIDO is used concomitantly with other products containing local anesthetic agents, the total amount of drug absorbed from all formulations must be considered.
ZTLIDO may not stick if it gets wet. Advise patients to avoid contact with water, such as bathing, swimming, or showering.
Instruct patients to wash hands immediately after handling ZTLIDO and to avoid contact with eyes [see Warnings and Precautions (5.6), Patient Counseling Information ( 17)] .
Instruct patients to store ZTLIDO inside the sealed envelope and to apply immediately after removal from the envelope. Advise them to store ZTLIDO out of the reach of children, pets, and others. Instruct patients to, after use, fold used ZTLIDO so that the adhesive side sticks to itself and safely discard used ZTLIDO or pieces of cut ZTLIDO where children and pets cannot get to them [see Warnings and Precautions ( 5.1), Patient Counseling Information ( 17)] .
Advise patients not to apply external heat sources, such as heating pads or electric blankets, directly to ZTLIDO because plasma lidocaine levels are increased. ZTLIDO can be applied, however, to the administration site after moderate heat exposure, such as 15 minutes of heating pad exposure on a medium setting [see Warnings and Precautions ( 5.2), Clinical Pharmacology ( 12.3), Patient Counseling Information ( 17)] .
ZTLIDO may be used during moderate exercise, such as biking for 30 minutes.
ZTLIDO topical systems that have lifted at the edges may be reattached by pressing firmly on the edges. If a ZTLIDO topical system comes off completely and will not stick to patient’s skin, it should be thrown away and a new ZTLIDO topical system should be applied for a total duration of 12 hours of used and new topical system together.
Apply ZTLIDO to intact skin to cover the most painful area. Apply the prescribed number of topical systems (maximum of 3), only once for up to 12 hours within a 24-hour period (12 hours on and 12 hours off). ZTLIDO may be cut into smaller sizes with scissors prior to removal of the release liner. Clothing may be worn over the area of application. Smaller areas of treatment are recommended in a debilitated patient, or a patient with impaired elimination.
If irritation or a burning sensation occurs during application, advise patients to remove ZTLIDO and do not reapply until the irritation subsides.
More about ZTlido (lidocaine topical)
- Side Effects
- During Pregnancy or Breastfeeding
- Drug Interactions
- Pricing & Coupons
- Drug class: topical anesthetics
- FDA Alerts (5)
- FDA Approval History