Remeron Dosage
Generic name: MIRTAZAPINE 15mg
Dosage form: tablet, film coated
Drug class: Tetracyclic antidepressants
Medically reviewed by Drugs.com. Last updated on Feb 24, 2025.
Recommended Dosage
The recommended starting dose of REMERON/REMERONSolTab is 15 mg once daily, administered orally, preferably in the evening prior to sleep. If patients do not have an adequate response to the initial 15 mg dose, increase the dose up to a maximum of 45 mg per day. Dose changes should not be made in intervals of less than 1 to 2 weeks to allow sufficient time for evaluation of response to a given dose.
Administration of REMERONSolTab
- The tablet should remain in the blister pack until the patient is ready to take it.
- The patient or caregiver should use dry hands to open the blister.
- As soon as the blister is opened, the tablet should be removed and placed on the patient's tongue.
- Use REMERONSolTab immediately after removal from its blister; once removed, it cannot be stored.
- The whole tablet should be placed on the tongue and allowed to disintegrate without chewing or crushing. Do not attempt to split the tablet.
- The tablet will disintegrate in saliva so that it can be swallowed.
Screen for Bipolar Disorder Prior to Starting REMERON/REMERONSolTab
Prior to initiating treatment with REMERON/REMERONSolTab or another antidepressant, screen patients for a personal or family history of bipolar disorder, mania, or hypomania.
Switching Patients to or from a Monoamine Oxidase Inhibitor Antidepressant
At least 14 days must elapse between discontinuation of a monoamine oxidase inhibitor (MAOI) antidepressant and initiation of REMERON/REMERONSolTab. In addition, at least 14 days must elapse after stopping REMERON/REMERONSolTab before starting an MAOI antidepressant.
Dosage Modifications Due to Drug Interactions
Strong CYP3A Inducers
An increase in dosage of REMERON/REMERONSolTab may be needed with concomitant strong CYP3A inducer (e.g., carbamazepine, phenytoin, rifampin) use. Conversely, a decrease in dosage of REMERON/REMERONSolTab may be needed if the CYP3A inducer is discontinued.
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Further information
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