Dicloxacillin Dosage

Medically reviewed by Drugs.com. Last updated on Aug 3, 2023.

Usual Adult Dose for Bronchitis

250 to 500 mg orally every 6 hours for 10 days, depending on the nature and severity of the infection.

Usual Adult Dose for Pharyngitis

250 mg orally every 6 hours for 10 days, depending on the nature and severity of the infection.

Usual Adult Dose for Pneumonia

500 mg orally every 6 hours for up to 21 days, depending on the nature and severity of the infection.

Usual Adult Dose for Skin or Soft Tissue Infection

500 mg orally every 6 hours for 7 days, or for 3 days after acute inflammation resolves, depending on the nature and severity of the infection.

Usual Adult Dose for Upper Respiratory Tract Infection

250 mg orally every 6 hours for 7 to 21 days, depending on the nature and severity of the infection.

Usual Pediatric Dose for Skin or Soft Tissue Infection

<40 kg: 3.125 to 6.25 mg/kg orally every 6 hours.

>40 kg: 125 to 250 mg orally every 6 hours.

Usual Pediatric Dose for Upper Respiratory Tract Infection

<40 kg: 3.125 to 6.25 mg/kg orally every 6 hours.

>40 kg: 125 to 250 mg orally every 6 hours.

Usual Pediatric Dose for Osteomyelitis

Following initial intravenous therapy:
>= 1 year:
<40 kg: 12.5 to 25 mg/kg orally every 6 hours, not to exceed 2000 mg/24 hours.

>40 kg: 250 mg orally every 6 hours, not to exceed 2000 mg/24 hours.

Usual Pediatric Dose for Pneumonia

<40 kg: 6.25 mg/kg orally every 6 hours.

>40 kg: 250 mg orally every 6 hours.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

Data not available

Precautions

Oral antibiotics are not recommended for patients with severe or life-threatening infections.

Dialysis

No adjustment recommended

Other Comments

Dicloxacillin is best absorbed when administered on an empty stomach, preferably 1 to 2 hours before meals.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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