Medically reviewed by Drugs.com. Last updated on Sep 4, 2023.
Use the lowest effective dosage of celecoxib for the shortest duration consistent with individual patient treatment goals [see Dosage and Administration (2.2) and Warnings and Precautions (5)] . Only 200 mg of celecoxib once daily is available with CONSENSI.
Start CONSENSI in adults at (amlodipine/celecoxib) 5 mg/200 mg orally once daily or 2.5 mg/200 mg in small, fragile, or elderly patients, or patients with mild hepatic insufficiency. Use 2.5 mg/200 mg when adding CONSENSI to other antihypertensive therapy.
Adjust amlodipine component dosage according to blood pressure goals. In general, wait 7 to 14 days between titration steps. If more rapid titration is clinically warranted, monitor closely. The maximum dose is 10 mg/200 mg once daily.
If analgesic therapy is no longer indicated, discontinue CONSENSI and initiate patient on alternative antihypertensive therapy, such as amlodipine monotherapy. If CONSENSI is stopped and replaced with an equal dose of amlodipine, monitor blood pressure carefully.
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