Chlorpheniramine / Phenylephrine Dosage

Medically reviewed by Drugs.com. Last updated on Apr 4, 2025.

Usual Adult Dose for Allergic Rhinitis

3.5 mg chlorpheniramine / 10 mg phenylephrine oral tablets: 1 tablet every 4 to 6 hours
Maximum dose: 6 tablets per 24 hours

4 mg chlorpheniramine, 10 mg phenylephrine / 5 mL oral liquid: 5 mL every 4 hours
Maximum dose: 6 doses per 24 hours

1 mg chlorpheniramine, 2.5 mg phenylephrine / 5 mL oral liquid: 5 mL every 6 hours
Maximum dose: 4 doses per 24 hours

Uses: Temporary relief of allergic rhinitis or other upper respiratory allergy symptoms (rhinorrhea, sneezing, itchy, watery eyes, nasal congestion, itchy nose or throat, sinus congestion and pressure)

Usual Adult Dose for Cold Symptoms

3.5 mg chlorpheniramine / 10 mg phenylephrine oral tablets: 1 tablet every 4 to 6 hours
Maximum dose: 6 tablets per 24 hours

4 mg chlorpheniramine, 10 mg phenylephrine / 5 mL oral liquid: 5 mL every 4 hours
Maximum dose: 6 doses per 24 hours

1 mg chlorpheniramine, 2.5 mg phenylephrine / 5 mL oral liquid: 5 mL every 6 hours
Maximum dose: 4 doses per 24 hours

Uses: Temporary relief of allergic rhinitis or other upper respiratory allergy symptoms (rhinorrhea, sneezing, itchy, watery eyes, nasal congestion, itchy nose or throat, sinus congestion and pressure)

Usual Pediatric Dose for Allergic Rhinitis

3.5 mg chlorpheniramine / 10 mg phenylephrine oral tablets:
12 years and over: 1 tablet every 4 to 6 hours
Maximum dose: 6 tablets per 24 hours

6 to 11 years: One half tablet every 4 to 6 hours
Maximum dose: 3 tablets per 24 hours

4 mg chlorpheniramine, 10 mg phenylephrine / 5 mL oral liquid:
12 years and over: 5 mL every 4 hours
6 to 11 years: 2.5 mL every 4 hours
Maximum dose: 6 doses per 24 hours

1 mg chlorpheniramine, 2.5 mg phenylephrine / 5 mL oral liquid:
12 years and over: 5 mL every 6 hours
6 to 11 years: 2.5 mL every 6 hours
Maximum dose: 4 doses per 24 hours

Uses: Temporary relief of allergic rhinitis or other upper respiratory allergy symptoms (rhinorrhea, sneezing, itchy, watery eyes, nasal congestion, itchy nose or throat, sinus congestion and pressure)

Usual Pediatric Dose for Cold Symptoms

3.5 mg chlorpheniramine / 10 mg phenylephrine oral tablets:
12 years and over: 1 tablet every 4 to 6 hours
Maximum dose: 6 tablets per 24 hours

6 to 11 years: One half tablet every 4 to 6 hours
Maximum dose: 3 tablets per 24 hours

4 mg chlorpheniramine, 10 mg phenylephrine / 5 mL oral liquid:
12 years and over: 5 mL every 4 hours
6 to 11 years: 2.5 mL every 4 hours
Maximum dose: 6 doses per 24 hours

1 mg chlorpheniramine, 2.5 mg phenylephrine / 5 mL oral liquid:
12 years and over: 5 mL every 6 hours
6 to 11 years: 2.5 mL every 6 hours
Maximum dose: 4 doses per 24 hours

Uses: Temporary relief of allergic rhinitis or other upper respiratory allergy symptoms (rhinorrhea, sneezing, itchy, watery eyes, nasal congestion, itchy nose or throat, sinus congestion and pressure)

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI
• Do not use to sedate a child
• Do not use for persistent or chronic cough (e.g. from smoking, asthma, emphysema) or if accompanied by excessive phlegm

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer