Chlorpheniramine / Phenylephrine Dosage
Medically reviewed by Drugs.com. Last updated on Apr 4, 2025.
Applies to the following strengths: 9 mg-25 mg; 4.5 mg-5 mg; 4.5 mg-5 mg/5 mL; 1 mg-2.5 mg/5 mL; 2 mg-5 mg/5 mL; 4 mg-10 mg; 4 mg-20 mg; 4 mg-20 mg/5 mL; 2 mg-5 mg; 8 mg-20 mg; 4 mg-10 mg/5 mL; 2 mg-6 mg/mL; 2 mg-5 mg/mL; 3 mg-10 mg; 1 mg-3.5 mg/mL; 4 mg-12.5 mg/5 mL; 3 mg-7.5 mg/5 mL; 1 mg-2 mg/mL; 1 mg-2.5 mg/mL; 3.5 mg-10 mg; 8 mg-10 mg/5 mL
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Allergic Rhinitis
3.5 mg chlorpheniramine / 10 mg phenylephrine oral tablets: 1 tablet every 4 to 6 hours
Maximum dose: 6 tablets per 24 hours
4 mg chlorpheniramine, 10 mg phenylephrine / 5 mL oral liquid: 5 mL every 4 hours
Maximum dose: 6 doses per 24 hours
1 mg chlorpheniramine, 2.5 mg phenylephrine / 5 mL oral liquid: 5 mL every 6 hours
Maximum dose: 4 doses per 24 hours
Uses: Temporary relief of allergic rhinitis or other upper respiratory allergy symptoms (rhinorrhea, sneezing, itchy, watery eyes, nasal congestion, itchy nose or throat, sinus congestion and pressure)
Usual Adult Dose for Cold Symptoms
3.5 mg chlorpheniramine / 10 mg phenylephrine oral tablets: 1 tablet every 4 to 6 hours
Maximum dose: 6 tablets per 24 hours
4 mg chlorpheniramine, 10 mg phenylephrine / 5 mL oral liquid: 5 mL every 4 hours
Maximum dose: 6 doses per 24 hours
1 mg chlorpheniramine, 2.5 mg phenylephrine / 5 mL oral liquid: 5 mL every 6 hours
Maximum dose: 4 doses per 24 hours
Uses: Temporary relief of allergic rhinitis or other upper respiratory allergy symptoms (rhinorrhea, sneezing, itchy, watery eyes, nasal congestion, itchy nose or throat, sinus congestion and pressure)
Usual Pediatric Dose for Allergic Rhinitis
3.5 mg chlorpheniramine / 10 mg phenylephrine oral tablets:
12 years and over: 1 tablet every 4 to 6 hours
Maximum dose: 6 tablets per 24 hours
6 to 11 years: One half tablet every 4 to 6 hours
Maximum dose: 3 tablets per 24 hours
4 mg chlorpheniramine, 10 mg phenylephrine / 5 mL oral liquid:
12 years and over: 5 mL every 4 hours
6 to 11 years: 2.5 mL every 4 hours
Maximum dose: 6 doses per 24 hours
1 mg chlorpheniramine, 2.5 mg phenylephrine / 5 mL oral liquid:
12 years and over: 5 mL every 6 hours
6 to 11 years: 2.5 mL every 6 hours
Maximum dose: 4 doses per 24 hours
Uses: Temporary relief of allergic rhinitis or other upper respiratory allergy symptoms (rhinorrhea, sneezing, itchy, watery eyes, nasal congestion, itchy nose or throat, sinus congestion and pressure)
Usual Pediatric Dose for Cold Symptoms
3.5 mg chlorpheniramine / 10 mg phenylephrine oral tablets:
12 years and over: 1 tablet every 4 to 6 hours
Maximum dose: 6 tablets per 24 hours
6 to 11 years: One half tablet every 4 to 6 hours
Maximum dose: 3 tablets per 24 hours
4 mg chlorpheniramine, 10 mg phenylephrine / 5 mL oral liquid:
12 years and over: 5 mL every 4 hours
6 to 11 years: 2.5 mL every 4 hours
Maximum dose: 6 doses per 24 hours
1 mg chlorpheniramine, 2.5 mg phenylephrine / 5 mL oral liquid:
12 years and over: 5 mL every 6 hours
6 to 11 years: 2.5 mL every 6 hours
Maximum dose: 4 doses per 24 hours
Uses: Temporary relief of allergic rhinitis or other upper respiratory allergy symptoms (rhinorrhea, sneezing, itchy, watery eyes, nasal congestion, itchy nose or throat, sinus congestion and pressure)
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI
- Do not use to sedate a child
- Do not use for persistent or chronic cough (e.g. from smoking, asthma, emphysema) or if accompanied by excessive phlegm
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
