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Carisoprodol Dosage

Medically reviewed by Last updated on Mar 18, 2022.

Applies to the following strengths: 350 mg; 250 mg

Usual Adult Dose for Muscle Spasm

250 to 350 mg orally 3 times a day and at bedtime
Duration of therapy: Up to 2 to 3 weeks

-This drug should only be used for short periods (up to 2 or 3 weeks) as there is inadequate evidence of effectiveness for more prolonged use and acute, painful musculoskeletal conditions are generally of short duration.

Use: For the relief of discomfort associated with acute, painful musculoskeletal conditions

Renal Dose Adjustments

Use with caution

Liver Dose Adjustments

Use with caution

Dose Adjustments

Patients with Reduced CYP450 2C19 Activity:
-Use with caution as higher exposure to carisoprodol and lower exposure to meprobamate (active metabolite) is expected; the clinical significance of this is not known.


Safety and efficacy have not been established in patients younger than 16 years or over 65 years.

US Controlled Substance: Schedule IV


Dialyzable by peritoneal and hemodialysis.

Other Comments

Administration advice:
Take orally with or without food

-Dependence, withdrawal, and abuse have been reported with prolonged use; duration of use should be limited to less than 3 weeks.

-Monitor for sedation
-Monitor for signs of abuse and overdose

Patient advice:
-Patients should avoid taking this drug prior to engaging in potentially hazardous activities as this drug has been associated with motor vehicle accidents.
-Patients should avoid alcohol while on this drug and check with their healthcare provider before taking other CNS depressants.
-Patients should be informed that this drug has been associated with cases of dependence, withdrawal, and abuse; use should be limited to less than 3 weeks duration.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.