Applies to the following strength(s): 350 mg ; 250 mg
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Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Muscle Spasm
250 to 350 mg orally 3 times a day and at bedtime
Duration of therapy: Up to 2 to 3 weeks
-This drug should only be used for short periods (up to 2 or 3 weeks) as there is inadequate evidence of effectiveness for more prolonged use and acute, painful musculoskeletal conditions are generally of short duration.
Use: For the relief of discomfort associated with acute, painful musculoskeletal conditions
Renal Dose Adjustments
Use with caution
Liver Dose Adjustments
Use with caution
Patients with Reduced CYP450 2C19 Activity:
-Use with caution as higher exposure to carisoprodol and lower exposure to meprobamate (active metabolite) is expected; the clinical significance of this is not known.
Safety and efficacy have not been established in patients younger than 16 years or over 65 years.
US Controlled Substance: Schedule IV
Dialyzable by peritoneal and hemodialysis.
Take orally with or without food
-Dependence, withdrawal, and abuse have been reported with prolonged use; duration of use should be limited to less than 3 weeks.
-Monitor for sedation
-Monitor for signs of abuse and overdose
-Patients should avoid taking this drug prior to engaging in potentially hazardous activities as this drug has been associated with motor vehicle accidents.
-Patients should avoid alcohol while on this drug and check with their healthcare provider before taking other CNS depressants.
-Patients should be informed that this drug has been associated with cases of dependence, withdrawal, and abuse; use should be limited to less than 3 weeks duration.
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