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Carisoprodol Dosage

Applies to the following strength(s): 350 mg250 mg

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Geriatric Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Muscle Spasm

250 to 350 mg orally 3 times a day and at bedtime
Duration of therapy: Up to 2 to 3 weeks

Comments:
-This drug should only be used for short periods (up to 2 or 3 weeks) as there is inadequate evidence of effectiveness for more prolonged use and acute, painful musculoskeletal conditions are generally of short duration.

Use: For the relief of discomfort associated with acute, painful musculoskeletal conditions

Usual Geriatric Dose for Muscle Spasm

Over 65 years: Safety and efficacy has not been established

Usual Pediatric Dose for Muscle Spasm

Age: 16 years or older:
250 to 350 mg orally 3 times a day and at bedtime
Duration of therapy: Up to 2 to 3 weeks

Comments:
-This drug should only be used for short periods (up to 2 or 3 weeks) as there is inadequate evidence of effectiveness for more prolonged use and acute, painful musculoskeletal conditions are generally of short duration.

Use: For the relief of discomfort associated with acute, painful musculoskeletal conditions

Renal Dose Adjustments

Use with caution

Liver Dose Adjustments

Use with caution

Dose Adjustments

Patients with Reduced CYP450 2C19 Activity:
-Use with caution as higher exposure to carisoprodol and lower exposure to meprobamate (active metabolite) is expected; the clinical significance of this is not known.

Precautions

Safety and efficacy have not been established in patients younger than 16 years or over 65 years.

US Controlled Substance: Schedule IV

Dialysis

Dialyzable by peritoneal and hemodialysis.

Other Comments

Administration advice:
Take orally with or without food

General:
-Dependence, withdrawal, and abuse have been reported with prolonged use; duration of use should be limited to less than 3 weeks.

Monitoring:
-Monitor for sedation
-Monitor for signs of abuse and overdose

Patient advice:
-Patients should avoid taking this drug prior to engaging in potentially hazardous activities as this drug has been associated with motor vehicle accidents.
-Patients should avoid alcohol while on this drug and check with their healthcare provider before taking other CNS depressants.
-Patients should be informed that this drug has been associated with cases of dependence, withdrawal, and abuse; use should be limited to less than 3 weeks duration.

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