Carisoprodol Dosage

Medically reviewed by Drugs.com. Last updated on Mar 18, 2025.

Applies to the following strengths: 350 mg; 250 mg

Usual Adult Dose for Muscle Spasm

250 to 350 mg orally 3 times a day and at bedtime
Duration of therapy: Up to 2 to 3 weeks

Comments:

This drug should only be used for short periods (up to 2 or 3 weeks) as there is inadequate evidence of effectiveness for more prolonged use and acute, painful musculoskeletal conditions are generally of short duration.

Use: For the relief of discomfort associated with acute, painful musculoskeletal conditions

Use with caution

Use with caution

Patients with Reduced CYP450 2C19 Activity:

Use with caution as higher exposure to carisoprodol and lower exposure to meprobamate (active metabolite) is expected; the clinical significance of this is not known.

Safety and efficacy have not been established in patients younger than 16 years or over 65 years.

US Controlled Substance: Schedule IV

Dialyzable by peritoneal and hemodialysis.

Administration advice:
Take orally with or without food

General:

Dependence, withdrawal, and abuse have been reported with prolonged use; duration of use should be limited to less than 3 weeks.

Monitoring:

Patient advice:

Patients should avoid taking this drug prior to engaging in potentially hazardous activities as this drug has been associated with motor vehicle accidents.
Patients should avoid alcohol while on this drug and check with their healthcare provider before taking other CNS depressants.
Patients should be informed that this drug has been associated with cases of dependence, withdrawal, and abuse; use should be limited to less than 3 weeks duration.