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Atenolol / Chlorthalidone Dosage

Medically reviewed by Last updated on Aug 3, 2023.

Applies to the following strengths: 50 mg-25 mg; 100 mg-25 mg

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Hypertension

Initial dose: Atenolol 50 mg-Chlorthalidone 25 mg orally once a day
Maintenance dose: Atenolol 50 to 100 mg-Chlorthalidone 25 mg orally once a day

Use: Treatment of hypertension if the fixed dose combination represents an appropriate dose for the individual patient.

Renal Dose Adjustments

CrCl greater than 35 mL/min/1.73 m2: No adjustment recommended
CrCl 15 to 35 mL/min/1.73 m2: Maximum dose: Atenolol 50 mg daily
CrCl less than 15 mL/min/1.73 m2: Maximum dose: Atenolol 50 mg every other day

If progressive renal impairment becomes evident: Discontinue this drug

Liver Dose Adjustments

Use with caution


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Storage requirements: Protect from light.


  • Metabolic: Serum electrolytes periodically

Patient advice:
  • Caution patients against interruption or cessation of therapy without a physician's advice.
  • If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential harm to the fetus.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.