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Albuterol Dosage

Medically reviewed on August 27, 2018.

Applies to the following strengths: 2 mg; 4 mg; 2 mg/5 mL; 90 mcg/inh; 5 mg/mL; 2.5 mg/3 mL (0.083%); with CFC 90 mcg/inh; 200 mcg; 8 mg; 0.63 mg/3 mL (0.021%); 1.25 mg/3 mL (0.042%)

Usual Adult Dose for Asthma - Acute

Intravenous infusion solution:
-Dilute 5 mL of this drug (1000 mcg/mL) in 500 mL of Sodium Chloride Injection, or Sodium Chloride and Dextrose.
-Infusion rates can be started at 5 mcg/min, and can be increased to 10 mcg/min and 20 mcg/min at 15 at 30 minute intervals, if necessary.

Nebulizer inhalation solution:
-2.5 mg three or four times a day by nebulization, over approximately 5 to 15 minutes.

Comments:
-Never inject the IV infusion undiluted. Do not administer in the same infusion with other medications.
-Check the IV infusion for clarity, particulate matter, precipitate, discoloration and leakage prior to administration.
-Discard unused infusion solution 24 hours after preparation.

Uses:
-Relief of severe bronchospasm associated with acute exacerbations of chronic bronchitis and bronchial asthma, and acute attack of bronchospasm
-Treatment of status asthmaticus

Usual Adult Dose for Chronic Obstructive Pulmonary Disease - Acute

Intravenous infusion solution:
-Dilute 5 mL of this drug (1000 mcg/mL) in 500 mL of Sodium Chloride Injection, or Sodium Chloride and Dextrose.
-Infusion rates can be started at 5 mcg/min, and can be increased to 10 mcg/min and 20 mcg/min at 15 at 30 minute intervals, if necessary.

Nebulizer inhalation solution:
-2.5 mg three or four times a day by nebulization, over approximately 5 to 15 minutes.

Comments:
-Never inject the IV infusion undiluted. Do not administer in the same infusion with other medications.
-Check the IV infusion for clarity, particulate matter, precipitate, discoloration and leakage prior to administration.
-Discard unused infusion solution 24 hours after preparation.

Uses:
-Relief of severe bronchospasm associated with acute exacerbations of chronic bronchitis and bronchial asthma, and acute attack of bronchospasm
-Treatment of status asthmaticus

Usual Adult Dose for Bronchitis

Intravenous infusion solution:
-Dilute 5 mL of this drug (1000 mcg/mL) in 500 mL of Sodium Chloride Injection, or Sodium Chloride and Dextrose.
-Infusion rates can be started at 5 mcg/min, and can be increased to 10 mcg/min and 20 mcg/min at 15 at 30 minute intervals, if necessary.

Nebulizer inhalation solution:
-2.5 mg three or four times a day by nebulization, over approximately 5 to 15 minutes.

Comments:
-Never inject the IV infusion undiluted. Do not administer in the same infusion with other medications.
-Check the IV infusion for clarity, particulate matter, precipitate, discoloration and leakage prior to administration.
-Discard unused infusion solution 24 hours after preparation.

Uses:
-Relief of severe bronchospasm associated with acute exacerbations of chronic bronchitis and bronchial asthma, and acute attack of bronchospasm
-Treatment of status asthmaticus

Usual Adult Dose for Bronchospasm Prophylaxis

Inhalation powder: 2 inhalations (180 mcg) orally 15 to 30 minutes before exercise
Inhalation capsule: 1 inhalation (200 mcg) 15 minutes before exercise

Uses: Prevention of exercise-induced bronchospasm

Usual Adult Dose for Asthma - Maintenance

Inhalation powder:
-1 or 2 inhalations (90 to 180 mcg) orally every 4 to 6 hours

Inhalation capsules:
-1 inhalation (200 mcg) orally every 4 to 6 hours
-Maximum dose: 4 inhalations (800 mcg) per day

Nebulizer inhalation solution:
-2.5 mg three or four times a day by nebulization, over approximately 5 to 15 minutes

Oral tablets:
Immediate-release tablets:
-Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated (maximum of 32 mg/day).
-Elderly patients and those sensitive to beta-adrenergic stimulators: The initial dosage should be restricted to 2 mg three or four times a day; dosage may be gradually increased up to 8 mg three or four times a day.

Extended-release tablets:
-Initial dose: 4 mg or 8 mg orally every 12 hours. Dosage may be cautiously increased stepwise under the control of the supervising physician to a maximum 32 mg/day in divided doses (e.g., every 12 hours). In unusual circumstances, such as adults of low body weight, use a starting dosage of 4 mg every 12 hours and progress to 8 mg every 12 hours according to response.

Oral syrup:
-Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated.
-Elderly patients and those sensitive to beta-adrenergic stimulators: The initial dosage should be restricted to 2 mg three or four times a day and individually adjusted thereafter.

Uses:
-Treatment or prevention of bronchospasm due to bronchial asthma, chronic bronchitis and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor
-Relief of bronchospasm in patients with reversible obstructive airway disease

Usual Adult Dose for Chronic Obstructive Pulmonary Disease - Maintenance

Inhalation powder:
-1 or 2 inhalations (90 to 180 mcg) orally every 4 to 6 hours

Inhalation capsules:
-1 inhalation (200 mcg) orally every 4 to 6 hours
-Maximum dose: 4 inhalations (800 mcg) per day

Nebulizer inhalation solution:
-2.5 mg three or four times a day by nebulization, over approximately 5 to 15 minutes

Oral tablets:
Immediate-release tablets:
-Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated (maximum of 32 mg/day).
-Elderly patients and those sensitive to beta-adrenergic stimulators: The initial dosage should be restricted to 2 mg three or four times a day; dosage may be gradually increased up to 8 mg three or four times a day.

Extended-release tablets:
-Initial dose: 4 mg or 8 mg orally every 12 hours. Dosage may be cautiously increased stepwise under the control of the supervising physician to a maximum 32 mg/day in divided doses (e.g., every 12 hours). In unusual circumstances, such as adults of low body weight, use a starting dosage of 4 mg every 12 hours and progress to 8 mg every 12 hours according to response.

Oral syrup:
-Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated.
-Elderly patients and those sensitive to beta-adrenergic stimulators: The initial dosage should be restricted to 2 mg three or four times a day and individually adjusted thereafter.

Uses:
-Treatment or prevention of bronchospasm due to bronchial asthma, chronic bronchitis and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor
-Relief of bronchospasm in patients with reversible obstructive airway disease

Usual Adult Dose for Reversible Airways Disease - Maintenance

Inhalation powder:
-1 or 2 inhalations (90 to 180 mcg) orally every 4 to 6 hours

Inhalation capsules:
-1 inhalation (200 mcg) orally every 4 to 6 hours
-Maximum dose: 4 inhalations (800 mcg) per day

Nebulizer inhalation solution:
-2.5 mg three or four times a day by nebulization, over approximately 5 to 15 minutes

Oral tablets:
Immediate-release tablets:
-Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated (maximum of 32 mg/day).
-Elderly patients and those sensitive to beta-adrenergic stimulators: The initial dosage should be restricted to 2 mg three or four times a day; dosage may be gradually increased up to 8 mg three or four times a day.

Extended-release tablets:
-Initial dose: 4 mg or 8 mg orally every 12 hours. Dosage may be cautiously increased stepwise under the control of the supervising physician to a maximum 32 mg/day in divided doses (e.g., every 12 hours). In unusual circumstances, such as adults of low body weight, use a starting dosage of 4 mg every 12 hours and progress to 8 mg every 12 hours according to response.

Oral syrup:
-Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated.
-Elderly patients and those sensitive to beta-adrenergic stimulators: The initial dosage should be restricted to 2 mg three or four times a day and individually adjusted thereafter.

Uses:
-Treatment or prevention of bronchospasm due to bronchial asthma, chronic bronchitis and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor
-Relief of bronchospasm in patients with reversible obstructive airway disease

Usual Pediatric Dose for Asthma - Acute

Inhalation powder and capsules:
Less than 4 years: Not indicated

4 years or older:
-Inhalation powder: 1 or 2 inhalations (90 or 180 mcg) orally every 4 to 6 hours
-Inhalation capsules:1 inhalation (200 mcg) orally every 4 to 6 hours. The total daily dose should not exceed 4 inhalations (800 mcg).

Nebulizer inhalation solution:
Less than 2 years: Not indicated

2 to 12 years:
-Less than 15 kg: 0.1 to 0.15 mg/kg/dose (one 3 mL unit-dose vial of 1.25 mg or 0.63 mg inhalation solution) by nebulization. The appropriate volume of the 0.5% inhalation solution should be diluted in sterile normal saline solution to a total of 3 mL prior administration. Dosing should not exceed 2.5 mg three to four times daily.
-15 kg or more: 2.5 mg (one 3 mL unit-dose vial of 0.0083%) three or four times a day by nebulization, over approximately 5 to 15 minutes. The 0.5% inhalation solution should be diluted with 2.5 mL of sterile normal saline solution

13 years or older:
-Inhalation solution 0.5% (5 mg/mL): 2.5 mg (0.5 mL diluted with 2.5 mL of sterile saline solution) three or four times a day by nebulization, over approximately 5 to 15 minutes

Use: Relief of bronchospasm in patients with reversible obstructive airway disease and acute attacks of bronchospasm

Usual Pediatric Dose for Chronic Obstructive Pulmonary Disease - Acute

Inhalation powder and capsules:
Less than 4 years: Not indicated

4 years or older:
-Inhalation powder: 1 or 2 inhalations (90 or 180 mcg) orally every 4 to 6 hours
-Inhalation capsules:1 inhalation (200 mcg) orally every 4 to 6 hours. The total daily dose should not exceed 4 inhalations (800 mcg).

Nebulizer inhalation solution:
Less than 2 years: Not indicated

2 to 12 years:
-Less than 15 kg: 0.1 to 0.15 mg/kg/dose (one 3 mL unit-dose vial of 1.25 mg or 0.63 mg inhalation solution) by nebulization. The appropriate volume of the 0.5% inhalation solution should be diluted in sterile normal saline solution to a total of 3 mL prior administration. Dosing should not exceed 2.5 mg three to four times daily.
-15 kg or more: 2.5 mg (one 3 mL unit-dose vial of 0.0083%) three or four times a day by nebulization, over approximately 5 to 15 minutes. The 0.5% inhalation solution should be diluted with 2.5 mL of sterile normal saline solution

13 years or older:
-Inhalation solution 0.5% (5 mg/mL): 2.5 mg (0.5 mL diluted with 2.5 mL of sterile saline solution) three or four times a day by nebulization, over approximately 5 to 15 minutes

Use: Relief of bronchospasm in patients with reversible obstructive airway disease and acute attacks of bronchospasm

Usual Pediatric Dose for Bronchitis

Inhalation powder and capsules:
Less than 4 years: Not indicated

4 years or older:
-Inhalation powder: 1 or 2 inhalations (90 or 180 mcg) orally every 4 to 6 hours
-Inhalation capsules:1 inhalation (200 mcg) orally every 4 to 6 hours. The total daily dose should not exceed 4 inhalations (800 mcg).

Nebulizer inhalation solution:
Less than 2 years: Not indicated

2 to 12 years:
-Less than 15 kg: 0.1 to 0.15 mg/kg/dose (one 3 mL unit-dose vial of 1.25 mg or 0.63 mg inhalation solution) by nebulization. The appropriate volume of the 0.5% inhalation solution should be diluted in sterile normal saline solution to a total of 3 mL prior administration. Dosing should not exceed 2.5 mg three to four times daily.
-15 kg or more: 2.5 mg (one 3 mL unit-dose vial of 0.0083%) three or four times a day by nebulization, over approximately 5 to 15 minutes. The 0.5% inhalation solution should be diluted with 2.5 mL of sterile normal saline solution

13 years or older:
-Inhalation solution 0.5% (5 mg/mL): 2.5 mg (0.5 mL diluted with 2.5 mL of sterile saline solution) three or four times a day by nebulization, over approximately 5 to 15 minutes

Use: Relief of bronchospasm in patients with reversible obstructive airway disease and acute attacks of bronchospasm

Usual Pediatric Dose for Bronchospasm Prophylaxis

Less than 4 years: Not indicated

4 years or older:
-Inhalation powder: 2 inhalations (180 mcg) orally 15 to 30 minutes before exercise
-Inhalation capsule: 1 inhalation (200 mcg) 15 minutes before exercise

Uses: Prevention of exercise-induced bronchospasm

Usual Pediatric Dose for Asthma - Maintenance

Inhalation powder and capsules:
Less than 4 years: Not indicated
4 years or older:
-Inhalation powder: 1 or 2 inhalations (90 or 180 mcg) orally every 4 to 6 hours
-Inhalation capsules:1 inhalation (200 mcg) orally every 4 to 6 hours. The total daily dose should not exceed 4 inhalations (800 mcg).

Nebulizer inhalation solution:
Less than 2 years: Not indicated
2 to 12 years:
-Less than 15 kg: 0.1 to 0.15 mg/kg/dose (one 3 mL unit-dose vial of 1.25 mg or 0.63 mg inhalation solution) by nebulization. The appropriate volume of the 0.5% inhalation solution should be diluted in sterile normal saline solution to a total of 3 mL prior administration. Dosing should not exceed 2.5 mg three to four times daily.
-15 kg or more: 2.5 mg (one 3 mL unit-dose vial of 0.0083%) three or four times a day by nebulization, over approximately 5 to 15 minutes. The 0.5% inhalation solution should be diluted with 2.5 mL of sterile normal saline solution

13 years or older:
-Inhalation solution 0.5% (5 mg/mL): 2.5 mg (0.5 mL diluted with 2.5 mL of sterile saline solution) three or four times a day by nebulization, over approximately 5 to 15 minutes.

Oral Tablets:
Less than 6 years: Not indicated
6 to 12 years:
-Immediate-release tablets: Initial dose: 2 mg orally three or four times a day. Dosage may be cautiously increased stepwise, but not to exceed 24 mg/day (given in divided doses).
-Extended-release tablets: Initial dose: 4 mg orally every 12 hours. Dosage may be cautiously increased stepwise under the control of the supervising physician to a maximum 24 mg/day in divided doses (e.g., every 12 hours).

13 years or older:
-Immediate-release tablets: Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated (maximum of 32 mg/day).
-Extended-release tablets: Initial dose: 4 mg or 8 mg orally every 12 hours. Dosage may be cautiously increased stepwise under the control of the supervising physician to a maximum 32 mg/day in divided doses (e.g., every 12 hours).

Oral syrup:
-Less than 2 years: Not indicated
-2 to 5 years: Initial dose: 0.1 mg/kg (do not exceed 2 mg) orally three times a day. Dosage may be increased stepwise to 0.2 mg/kg three times a day. A maximum dose of 4 mg three times a day should not be exceeded.
-6 to 14 years: Initial dose: 2 mg orally three or four times a day. Dosage may be cautiously increased stepwise, but not exceed 24 mg/day (in divided doses).
-15 years or older: Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated.

Uses: Treatment or prevention of bronchospasm due to bronchial asthma, chronic bronchitis and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor

Usual Pediatric Dose for Chronic Obstructive Pulmonary Disease - Maintenance

Inhalation powder and capsules:
Less than 4 years: Not indicated
4 years or older:
-Inhalation powder: 1 or 2 inhalations (90 or 180 mcg) orally every 4 to 6 hours
-Inhalation capsules:1 inhalation (200 mcg) orally every 4 to 6 hours. The total daily dose should not exceed 4 inhalations (800 mcg).

Nebulizer inhalation solution:
Less than 2 years: Not indicated
2 to 12 years:
-Less than 15 kg: 0.1 to 0.15 mg/kg/dose (one 3 mL unit-dose vial of 1.25 mg or 0.63 mg inhalation solution) by nebulization. The appropriate volume of the 0.5% inhalation solution should be diluted in sterile normal saline solution to a total of 3 mL prior administration. Dosing should not exceed 2.5 mg three to four times daily.
-15 kg or more: 2.5 mg (one 3 mL unit-dose vial of 0.0083%) three or four times a day by nebulization, over approximately 5 to 15 minutes. The 0.5% inhalation solution should be diluted with 2.5 mL of sterile normal saline solution

13 years or older:
-Inhalation solution 0.5% (5 mg/mL): 2.5 mg (0.5 mL diluted with 2.5 mL of sterile saline solution) three or four times a day by nebulization, over approximately 5 to 15 minutes.

Oral Tablets:
Less than 6 years: Not indicated
6 to 12 years:
-Immediate-release tablets: Initial dose: 2 mg orally three or four times a day. Dosage may be cautiously increased stepwise, but not to exceed 24 mg/day (given in divided doses).
-Extended-release tablets: Initial dose: 4 mg orally every 12 hours. Dosage may be cautiously increased stepwise under the control of the supervising physician to a maximum 24 mg/day in divided doses (e.g., every 12 hours).

13 years or older:
-Immediate-release tablets: Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated (maximum of 32 mg/day).
-Extended-release tablets: Initial dose: 4 mg or 8 mg orally every 12 hours. Dosage may be cautiously increased stepwise under the control of the supervising physician to a maximum 32 mg/day in divided doses (e.g., every 12 hours).

Oral syrup:
-Less than 2 years: Not indicated
-2 to 5 years: Initial dose: 0.1 mg/kg (do not exceed 2 mg) orally three times a day. Dosage may be increased stepwise to 0.2 mg/kg three times a day. A maximum dose of 4 mg three times a day should not be exceeded.
-6 to 14 years: Initial dose: 2 mg orally three or four times a day. Dosage may be cautiously increased stepwise, but not exceed 24 mg/day (in divided doses).
-15 years or older: Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated.

Uses: Treatment or prevention of bronchospasm due to bronchial asthma, chronic bronchitis and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor

Usual Pediatric Dose for Reversible Airways Disease - Maintenance

Inhalation powder and capsules:
Less than 4 years: Not indicated
4 years or older:
-Inhalation powder: 1 or 2 inhalations (90 or 180 mcg) orally every 4 to 6 hours
-Inhalation capsules:1 inhalation (200 mcg) orally every 4 to 6 hours. The total daily dose should not exceed 4 inhalations (800 mcg).

Nebulizer inhalation solution:
Less than 2 years: Not indicated
2 to 12 years:
-Less than 15 kg: 0.1 to 0.15 mg/kg/dose (one 3 mL unit-dose vial of 1.25 mg or 0.63 mg inhalation solution) by nebulization. The appropriate volume of the 0.5% inhalation solution should be diluted in sterile normal saline solution to a total of 3 mL prior administration. Dosing should not exceed 2.5 mg three to four times daily.
-15 kg or more: 2.5 mg (one 3 mL unit-dose vial of 0.0083%) three or four times a day by nebulization, over approximately 5 to 15 minutes. The 0.5% inhalation solution should be diluted with 2.5 mL of sterile normal saline solution

13 years or older:
-Inhalation solution 0.5% (5 mg/mL): 2.5 mg (0.5 mL diluted with 2.5 mL of sterile saline solution) three or four times a day by nebulization, over approximately 5 to 15 minutes.

Oral Tablets:
Less than 6 years: Not indicated
6 to 12 years:
-Immediate-release tablets: Initial dose: 2 mg orally three or four times a day. Dosage may be cautiously increased stepwise, but not to exceed 24 mg/day (given in divided doses).
-Extended-release tablets: Initial dose: 4 mg orally every 12 hours. Dosage may be cautiously increased stepwise under the control of the supervising physician to a maximum 24 mg/day in divided doses (e.g., every 12 hours).

13 years or older:
-Immediate-release tablets: Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated (maximum of 32 mg/day).
-Extended-release tablets: Initial dose: 4 mg or 8 mg orally every 12 hours. Dosage may be cautiously increased stepwise under the control of the supervising physician to a maximum 32 mg/day in divided doses (e.g., every 12 hours).

Oral syrup:
-Less than 2 years: Not indicated
-2 to 5 years: Initial dose: 0.1 mg/kg (do not exceed 2 mg) orally three times a day. Dosage may be increased stepwise to 0.2 mg/kg three times a day. A maximum dose of 4 mg three times a day should not be exceeded.
-6 to 14 years: Initial dose: 2 mg orally three or four times a day. Dosage may be cautiously increased stepwise, but not exceed 24 mg/day (in divided doses).
-15 years or older: Initial dose: 2 mg or 4 mg orally three or four times a day. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a day as tolerated.

Uses: Treatment or prevention of bronchospasm due to bronchial asthma, chronic bronchitis and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Inhalation solution and oral syrup:
Safety and efficacy have not been established in patients younger than 2 years.

Inhalation powder and inhalation capsules:
Safety and efficacy have not been established in patients younger than 4 years.

Immediate and extended release oral tablet:
Safety and efficacy have not been established in patients younger than 6 years.

Intravenous infusion:
Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Inhalation solution, powder, and capsules are for oral inhalation only.
-More frequent administration or a larger number of inhalations are not recommended.
-Oral tablets should not be chewed or crushed; tablets should be swallowed whole with liquids.
-The manufacturer product information should be consulted for instructions of use.

Inhalation powder HFA:
-Prime the inhalation device before using for the first time, when the inhaler has not been used for more than 2 weeks, or when the inhaler has been dropped.
-To prime, release 4 sprays into the air away from the face, shaking well before each spray.
-To ensure proper dosing and to prevent actuator orifice blockage, wash the actuator with warm water and let it air-dry completely at least once a week.

Inhalation powder RESPICLICK:
-Inhaler does not require priming.
-Keep the inhaler clean and dry at all times. Never wash or put any part of the inhaler in water.

Switching from oral immediate release to extended release products:
-The administration of one 4 mg extended-release tablet every 12 hours is comparable to one 2 mg immediate tablet every 6 hours. Multiples of this regimen up to the maximum recommended daily dose also apply.

Patient advice:
-Other inhaled drugs and asthma medications should be taken only as directed by the physician while taking this drug.
-Seek medical advice if short-acting relief bronchodilator treatment becomes less effective, or more inhalations than usual is required. Do not increase the dose or its frequency of administration.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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