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Albuterol Pregnancy and Breastfeeding Warnings

Albuterol is also known as: AccuNeb, Airet, ProAir HFA, ProAir RespiClick, Proventil, Proventil HFA, Respirol, Ventolin, Ventolin HFA, Volmax, Vospire ER

Albuterol Pregnancy Warnings

Albuterol has been assigned to pregnancy category C by the FDA. Animal studies have demonstrated a teratogenic effect. Albuterol is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.

One study of 12 pregnant asthmatics between 33 and 39 weeks gestation showed no significant effect of inhaled albuterol on maternal or fetal circulations. For the two hours immediately following a dose of two deep inhalations of 0.5% solution, no significant effect was seen on maternal blood pressure or heart rate, umbilical artery systolic/diastolic ratio, fetal aortic velocities or heart rate.

See references

Albuterol Breastfeeding Warnings

There are no data on the excretion of albuterol into human milk.

See references

References for pregnancy information

  1. Lind T, Godfrey KA, Gerrard J, Bryson MR "Continuous salbutamol infusion over 17 weeks to pre-empt premature labour." Lancet 2 (1980): 1165-6
  2. Tan SN "Peri-partum pulmonary oedema." Anaesth Intensive Care 19 (1991): 111-3
  3. Watson NA, Morgan B "Pulmonary oedema and salbutamol in preterm labour. Case report and literature review." Br J Obstet Gynaecol 96 (1989): 1445-8
  4. "Product Information. Proventil (albuterol)." Schering Laboratories, Kenilworth, NJ.
  5. Mcdonald CF, Burdon JGW "Asthma in pregnancy and lactation - a position paper for the thoracic society of australia and new zealand." Med J Aust 165 (1996): 485-8
  6. Davies AE, Robertson MJ "Pulmonary oedema after the administration of intravenous salbutamol and ergometrine. Case report." Br J Obstet Gynaecol 87 (1980): 539-41
  7. Rayburn WF, Atkinson BD, Gilbert K, Turnbull GL "Short-term effects of inhaled albuterol on maternal and fetal circulations." Am J Obstet Gynecol 171 (1994): 770-3
  8. Hawker F "Five cases of pulmonary oedema associated with beta 2-sympathomimetic treatment of premature labour." Anaesth Intensive Care 12 (1984): 159-62
  9. Dombrowski MP "Pharmacologic therapy of asthma during pregnancy." Obstet Gynecol Clin North Am 24 (1997): 559
  10. Lunell NO, Joelsson I, Bjorkman U, Lamb P, Persson B "The use of salbutamol in obstetrics." Acta Obstet Gynecol Scand 55 (1976): 333-6
  11. Martin AJ "Severe unwanted effects associated with betasympathomimetics when used in the treatment of premature labour: causes, incidence and preventative measures." Br J Clin Pract 35 (1981): 325-9
  12. "Product Information. Ventolin (albuterol)." Glaxo Wellcome, Research Triangle Park, NC.

References for breastfeeding information

  1. Mcdonald CF, Burdon JGW "Asthma in pregnancy and lactation - a position paper for the thoracic society of australia and new zealand." Med J Aust 165 (1996): 485-8
  2. "Product Information. Proventil (albuterol)." Schering Laboratories, Kenilworth, NJ.
  3. "Product Information. Ventolin (albuterol)." Glaxo Wellcome, Research Triangle Park, NC.

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