Cytotec (misoprostol) Disease Interactions
There are 2 disease interactions with Cytotec (misoprostol):
Misoprostol (applies to Cytotec) cardiovascular disease
Moderate Potential Hazard, Moderate plausibility.
Caution should be employed when administering misoprostol to patients with preexisting cardiovascular disease.
Misoprostol (applies to Cytotec) diarrhea
Moderate Potential Hazard, High plausibility. Applicable conditions: Inflammatory Bowel Disease, Dehydration
Diarrhea may occur in up to 40% of patients receiving misoprostol. Misoprostol should be administered cautiously in patients with underlying conditions such as inflammatory bowel disease and dehydration. Careful monitoring during therapy is recommended.
- Wildeman RA "Focus on misoprostol: review of worldwide safety data." Clin Invest Med 10 (1987): 243-5
- "Product Information. Cytotec (misoprostol)." Searle, Skokie, IL.
Cytotec (misoprostol) drug interactions
There are 13 drug interactions with Cytotec (misoprostol)
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- Drug class: miscellaneous GI agents
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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