Robaxin Disease Interactions
There are 2 disease interactions with Robaxin (methocarbamol).
Methocarbamol (parenteral) (applies to Robaxin) renal dysfunction
Major Potential Hazard, Moderate plausibility.
The injectable formulation of methocarbamol is contraindicated for use in patients with impaired renal function due to the nephrotoxic potential of polyethylene glycol (PEG) 300 present in the vehicle. Quantities of PEG 300 much greater than that found in recommended doses of injectable methocarbamol have increased preexisting acidosis and urea retention in patients with renal impairment.
Methocarbamol (parenteral) (applies to Robaxin) seizures
Moderate Potential Hazard, Moderate plausibility.
Seizures have occurred during the intravenous administration of methocarbamol. In some cases, the patient had a known history of epilepsy, and the psychic trauma of the procedure may have been a contributing factor. Nevertheless, therapy with the injectable formulation of methocarbamol should be administered cautiously in patients with a history of epilepsy.
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Robaxin drug interactions
There are 346 drug interactions with Robaxin (methocarbamol).
Robaxin alcohol/food interactions
There is 1 alcohol/food interaction with Robaxin (methocarbamol).
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- Drug class: skeletal muscle relaxants
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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