Eszopiclone Disease Interactions
There are 3 disease interactions with eszopiclone:
Anxiolytics/sedatives/hypnotics (Includes eszopiclone) ↔ depression
Severe Potential Hazard, Moderate plausibility. Applies to: Depression
A variety of abnormal thinking and behavior changes have been reported to occur in association with the use of most anxiolytics, sedatives and hypnotics. Some of these changes include decreased inhibition, aggressiveness, agitation, and hallucinations. These drugs can cause or exacerbate mental depression and cause suicidal behavior and ideation. Therapy with these drugs should be administered cautiously in patients with a history of depression or other psychiatric disorders. Patients should be monitored for any changes in mood or behavior. It may be prudent to refrain from dispensing large quantities of medication to these patients.
- "Product Information. Ambien (zolpidem)." sanofi-aventis, Bridgewater, NJ.
- "Product Information. Placidyl (ethchlorvynol)." Abbott Pharmaceutical, Abbott Park, IL.
- "Product Information. Equanil (meprobamate)." Wallace Laboratories, Cranbury, NJ.
- "Product Information. Aquachloral Supprettes (chloral hydrate)." Medisca, Plattsburg, NY.
- "Product Information. Sonata (zaleplon)" Wyeth-Ayerst Laboratories, Philadelphia, PA.
Anxiolytics/sedatives/hypnotics (Includes eszopiclone) ↔ glaucoma
Moderate Potential Hazard, Moderate plausibility. Applies to: Glaucoma/Intraocular Hypertension, Urinary Retention
Some hypnotic drugs can have an anticholinergic effect and should be used with caution in patients with glaucoma, and trouble urinating due to retention or enlarged prostate.
Anxiolytics/sedatives/hypnotics (Includes eszopiclone) ↔ liver disease
Moderate Potential Hazard, Moderate plausibility. Applies to: Liver Disease
In general, anxiolytics, sedatives and hypnotics are extensively metabolized by the liver. Their plasma clearance may be decreased and their half-life prolonged in patients with impaired hepatic function. Therapy with these drugs should be administered cautiously in patients with liver disease (some are not recommended in severe liver impairment), and the dosage should be adjusted accordingly. Laboratory testing is recommended prior and during treatment.
Eszopiclone drug interactions
There are 703 drug interactions with eszopiclone
Eszopiclone alcohol/food interactions
There is 1 alcohol/food interaction with eszopiclone
More about eszopiclone
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- 278 Reviews
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- FDA Alerts (2)
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.