Tacrolimus Compared to Alternatives
| Tacrolimus Remove Tacrolimus from your drug comparison | CellCept Remove CellCept from your drug comparison | Prograf Remove Prograf from your drug comparison |
|---|
| Tacrolimus Remove Tacrolimus from your drug comparison | CellCept mycophenolate mofetil Remove CellCept from your drug comparison | Prograf tacrolimus Remove Prograf from your drug comparison | ||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Prescribed for Organ Transplant - Rejection Prophylaxis, Organ Transplant - Rejection Reversal. May also be prescribed off label for Nephrotic Syndrome, Graft-versus-host disease, Crohn's Disease. |
Prescribed for Nephrotic Syndrome, Organ Transplant - Rejection Prophylaxis. CellCept may also be used for purposes not listed in this medication guide. |
Prescribed for Organ Transplant - Rejection Prophylaxis, Organ Transplant - Rejection Reversal. Prograf may also be used for purposes not listed in this medication guide. |
Choose a suggestion belowPopular Comparisons
Organ Transplant, Rejection Prophylaxis
|
|||||||||||||||||||||||
|
Prescription only |
Prescription only |
Prescription only |
||||||||||||||||||||||||
Ratings & ReviewsRecent helpful reviews |
||||||||||||||||||||||||||
|
8.0
For Organ Transplant, Rejection Prophylaxis: I read where prograf does not work well on people of color. I started with 12 pills a day weakened my entire body. Now on 8 pills a day, every so often it weakens my body. Cant stand for long periods of time, I get tired and feel very weak. right now searching for an answer, dr. contacted today |
8.4
For Organ Transplant, Rejection Prophylaxis: But too expensive. I'm 27 years old with no insurance and I'm paying close to $1000 a month. For Organ Transplant, Rejection Prophylaxis: I had a liver transplant Feb '06 and have taken 1000mg twice a day now for a couple years. Before that dosage changed a bit to get correct dosage. I also take tacrolimus (prograf 1mg twice a day) I have had no side effects--expensive but luckily I have a plan. |
8.3
For Organ Transplant, Rejection Prophylaxis: I started taking 3mg/day Prograf almost a week ago for my heart transplant. I was on cyclosporin but was having lots of muscle pain and cramps from the cyclosporin. Since starting the Prograg I've been itching non stop. Its apparently one of the side effects. I've also gained some fluid in my legs and hands. Another side effect. I hope the itching goes away soon or I'll have to switch to something else. For Organ Transplant, Rejection Prophylaxis: I have been using Prograf for 4 years now. 1 mg in the AM and 1 mg in PM. Last year or 3rd year into this treatment I had 2 episodes with squamous cell carcinoma, which were both removed. |
||||||||||||||||||||||||
Drug Class |
||||||||||||||||||||||||||
Side Effects |
||||||||||||||||||||||||||
|
Commonly reported side effects include: opportunistic infection, diabetes mellitus, infection, headache, hyperglycemia, hyperkalemia, increased blood urea nitrogen, increased serum creatinine, mental status changes, nephrotoxicity, sensation disorder, tremor. See the full tacrolimus side effects document. |
Common side effects include: asthma, herpes simplex infection, infection, metabolic acidosis, oral candidiasis, pleural effusion, respiratory tract infection, systemic cytomegalovirus disease, urinary tract infection, viremia, abdominal pain, acne vulgaris, anemia, anxiety, asthenia, back pain, cardiovascular disorder, chest pain, constipation, cough, depression, diarrhea, disorder of integument, drowsiness, dyspepsia, dyspnea, edema, fever, headache, hypercholesterolemia, hyperlipidemia, hypertension, hypertonia, hyperuricemia, hypervolemia, hypokalemia, hypotension, increased lactate dehydrogenase, increased serum alanine aminotransferase, increased serum aspartate aminotransferase, increased serum creatinine, leukopenia, lower limb cramp, myalgia, myasthenia, nausea, pain, paresthesia, peripheral edema, pulmonary disease, rhinitis, sinusitis, tachycardia, thrombocytopenia, tremor, vomiting, weight gain, chills, flatulence. See the full CellCept side effects document. |
Common side effects include: opportunistic infection, diabetes mellitus, infection, headache, hyperglycemia, hyperkalemia, increased blood urea nitrogen, increased serum creatinine, mental status changes, nephrotoxicity, sensation disorder, tremor. See the full Prograf side effects document. |
||||||||||||||||||||||||
Pricing and Coupons* Prices are without insurance |
||||||||||||||||||||||||||
View all tacrolimus prices |
View all CellCept prices and generic prices |
View all Prograf prices and generic prices |
||||||||||||||||||||||||
Generic Availability |
||||||||||||||||||||||||||
|
Yes (this medicine) |
||||||||||||||||||||||||||
Dosage Form(s) Available |
||||||||||||||||||||||||||
|
|
|
||||||||||||||||||||||||
Brand Names |
||||||||||||||||||||||||||
| Astagraf XL, Envarsus XR, Hecoria, Prograf |
N/A |
Other tacrolimus brands include: Astagraf XL, Envarsus XR, Hecoria | ||||||||||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
||||||||||||||||||||||||||
|
21.2 hours |
18 hours |
21.2 hours |
||||||||||||||||||||||||
CSA Schedule**View glossary of terms. |
||||||||||||||||||||||||||
|
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
||||||||||||||||||||||||
Pregnancy Category |
||||||||||||||||||||||||||
|
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
||||||||||||||||||||||||
FDA Alerts |
||||||||||||||||||||||||||
Drug Interactions |
||||||||||||||||||||||||||
|
A total of 681 drugs are known to interact with tacrolimus:
|
A total of 260 drugs are known to interact with CellCept:
|
A total of 681 drugs are known to interact with Prograf:
|
||||||||||||||||||||||||
Alcohol/Food/Lifestyle Interactions |
||||||||||||||||||||||||||
|
No results found - however, this does not necessarily mean no warnings exist. Always consult with your doctor or pharmacist. |
|
||||||||||||||||||||||||
Disease Interactions |
||||||||||||||||||||||||||
First Approval Date |
||||||||||||||||||||||||||
|
April 08, 1994 |
May 03, 1995 |
April 08, 1994 |
||||||||||||||||||||||||
WADA ClassView World Anti-Doping Agency classifications. |
||||||||||||||||||||||||||
|
N/A |
N/A |
N/A |
||||||||||||||||||||||||
More Information |
||||||||||||||||||||||||||
Consumer Resources |
||||||||||||||||||||||||||
Professional Resources |
||||||||||||||||||||||||||
Related Treatment Guide |
||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Organ Transplant, Rejection Prophylaxis: Tacrolimus (aka FK506) saved my first renal graft in 1994. Second renal graft in 2016 and tacrolimus still working great. No side effects noted in 20+years of use except if dose gets to high some hand tremors.