Tacrolimus Alternatives Compared
| Tacrolimus | CellCept | Prograf |
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| Tacrolimus | CellCept mycophenolate mofetil | Prograf tacrolimus |
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Prescribed for Organ Transplant - Rejection Prophylaxis, Organ Transplant - Rejection Reversal. May also be prescribed off label for Nephrotic Syndrome, Graft-versus-host disease, Crohn's Disease. |
Prescribed for Nephrotic Syndrome, Organ Transplant - Rejection Prophylaxis. CellCept may also be used for purposes not listed in this medication guide. |
Prescribed for Organ Transplant - Rejection Prophylaxis, Organ Transplant - Rejection Reversal. Prograf may also be used for purposes not listed in this medication guide. |
Choose a suggestion below Organ Transplant, Rejection Prophylaxis
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| More about Tacrolimus | More about CellCept (mycophenolate mofetil) | More about Prograf (tacrolimus) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Tacrolimus has an average rating of 8.0 out of 10 from a total of 45 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 10% reported a negative effect. |
CellCept has an average rating of 8.5 out of 10 from a total of 12 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 3% reported a negative effect. |
Prograf has an average rating of 8.0 out of 10 from a total of 27 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 8% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include: opportunistic infection, diabetes mellitus, infection, headache, hyperglycemia, hyperkalemia, increased blood urea nitrogen, increased serum creatinine, mental status changes, nephrotoxicity, sensation disorder, tremor. See the full tacrolimus side effects document. |
Common side effects include: asthma, herpes simplex infection, infection, metabolic acidosis, oral candidiasis, pleural effusion, respiratory tract infection, systemic cytomegalovirus disease, urinary tract infection, viremia, abdominal pain, acne vulgaris, anemia, anxiety, asthenia, back pain, cardiovascular disorder, chest pain, constipation, cough, depression, diarrhea, disorder of integument, drowsiness, dyspepsia, dyspnea, edema, fever, headache, hypercholesterolemia, hyperlipidemia, hypertension, hypertonia, hyperuricemia, hypervolemia, hypokalemia, hypotension, increased lactate dehydrogenase, increased serum alanine aminotransferase, increased serum aspartate aminotransferase, increased serum creatinine, leukopenia, lower limb cramp, myalgia, myasthenia, nausea, pain, paresthesia, peripheral edema, pulmonary disease, rhinitis, sinusitis, tachycardia, thrombocytopenia, tremor, vomiting, weight gain, chills, flatulence. See the full CellCept side effects document. |
Common side effects include: opportunistic infection, diabetes mellitus, infection, headache, hyperglycemia, hyperkalemia, increased blood urea nitrogen, increased serum creatinine, mental status changes, nephrotoxicity, sensation disorder, tremor. See the full Prograf side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all tacrolimus prices |
View all CellCept prices and generic prices |
View all Prograf prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Astagraf XL, Envarsus XR, Prograf |
N/A |
Other tacrolimus brands include: Astagraf XL, Envarsus XR | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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21.2 hours |
18 hours |
21.2 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 772 drugs are known to interact with tacrolimus:
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A total of 297 drugs are known to interact with CellCept:
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A total of 772 drugs are known to interact with Prograf:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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April 08, 1994 |
May 03, 1995 |
April 08, 1994 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.