Comparing Prograf vs Tacrolimus

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Prograf tacrolimus

Tacrolimus

Prescribed for Organ Transplant - Rejection Prophylaxis, Organ Transplant - Rejection Reversal. Prograf may also be used for purposes not listed in this medication guide.

Prescribed for Organ Transplant - Rejection Prophylaxis, Organ Transplant - Rejection Reversal. May also be prescribed off label for Nephrotic Syndrome, Graft-versus-host disease, Crohn's Disease.

Prescription only

Ratings & Reviews

View all 27 reviews

View all 45 reviews

Drug Class

Calcineurin inhibitors

Calcineurin inhibitors

Side Effects

Common side effects include: opportunistic infection, diabetes mellitus, infection, headache, hyperglycemia, hyperkalemia, increased blood urea nitrogen, increased serum creatinine, mental status changes, nephrotoxicity, sensation disorder, and tremor.

See the full Prograf side effects document.

Commonly reported side effects include: opportunistic infection, diabetes mellitus, infection, headache, hyperglycemia, hyperkalemia, increased blood urea nitrogen, increased serum creatinine, mental status changes, nephrotoxicity, sensation disorder, and tremor.

See the full tacrolimus side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	100 capsule
Dosage	1 mg
Per Unit^*	$6.39 - $6.58
Cost^*	$639.28 - $658.18

View all Prograf prices and generic prices

Quantity	100 each
Dosage	1 mg
Per Unit^*	$1.24 - $2.00
Cost^*	$124.33 - $199.61

View all tacrolimus prices

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Generic Availability

Yes

Yes (this medicine)

Dosage Form(s) Available

Intravenous solution
Oral capsule
Oral granule for reconstitution

Oral capsule

Brand Names

Other tacrolimus brands include: Astagraf XL, Envarsus XR Astagraf XL, Envarsus XR, Prograf

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

21.2 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Drug Interactions

A total of 752 drugs are known to interact with Prograf:

231 major drug interactions (857 brand and generic names)
504 moderate drug interactions (1876 brand and generic names)
17 minor drug interactions (129 brand and generic names)

A total of 752 drugs are known to interact with tacrolimus:

231 major drug interactions (857 brand and generic names)
504 moderate drug interactions (1876 brand and generic names)
17 minor drug interactions (129 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Tacrolimus should be taken on a consistent schedule before or after you eat at the same times each... View more

Tacrolimus should be taken on a consistent schedule before or after you eat at the same times each... View more

Disease Interactions

First Approval Date

April 08, 1994

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Prescribing Information

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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