Comparing Prograf vs Rapamune
| Prograf (tacrolimus) | Rapamune (sirolimus) |
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| Prograf (tacrolimus) | Rapamune (sirolimus) |
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Prescription only
Prescribed for Organ Transplant - Rejection Reversal, Organ Transplant - Rejection Prophylaxis. Prograf may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Lymphangioleiomyomatosis, Organ Transplant - Rejection Prophylaxis. Rapamune may also be used for purposes not listed in this medication guide. |
Related suggestions Organ Transplant, Rejection Prophylaxis
Popular comparisons
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| More about Prograf (tacrolimus) | More about Rapamune (sirolimus) | ||||||||
| Ratings & Reviews | |||||||||
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Prograf has an average rating of 8.1 out of 10 from a total of 28 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 7% reported a negative effect. |
Rapamune has an average rating of 7.0 out of 10 from a total of 3 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 33% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
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View all Prograf side effects |
View all Rapamune side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Prograf prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other tacrolimus brands include: Astagraf XL, Envarsus XR |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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21.2 hours |
78 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 880 drugs are known to interact with Prograf:
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A total of 727 drugs are known to interact with Rapamune:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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April 08, 1994 |
September 15, 1999 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.