Comparing Prograf vs Rapamune
| Prograf (tacrolimus) | Rapamune (sirolimus) |
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| Prograf (tacrolimus) | Rapamune (sirolimus) |
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Prescription only
Prescribed for Organ Transplant - Rejection Reversal, Organ Transplant - Rejection Prophylaxis. Prograf may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Lymphangioleiomyomatosis, Organ Transplant - Rejection Prophylaxis. Rapamune may also be used for purposes not listed in this medication guide. |
Related suggestions Organ Transplant, Rejection Prophylaxis
Popular comparisons
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| More about Prograf (tacrolimus) | More about Rapamune (sirolimus) | ||||||||
| Ratings & Reviews | |||||||||
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Prograf has an average rating of 8.1 out of 10 from a total of 28 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 7% reported a negative effect. |
Rapamune has an average rating of 7.0 out of 10 from a total of 3 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 33% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
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View all Prograf side effects |
View all Rapamune side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Prograf prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other tacrolimus brands include: Astagraf XL, Envarsus XR |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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21.2 hours |
78 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 874 drugs are known to interact with Prograf:
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A total of 721 drugs are known to interact with Rapamune:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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April 08, 1994 |
September 15, 1999 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Envarsus XR
Envarsus XR is used for organ transplant, rejection prophylaxis
Astagraf XL
Astagraf XL is used for organ transplant, rejection prophylaxis
Botox
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Gengraf
Gengraf is used for organ transplant, rejection prophylaxis, psoriasis, rheumatoid arthritis
Lupkynis
Lupkynis is used to treat active lupus nephritis in adults with SLE. Lupkynis for lupus is a ...
Neoral
Neoral is used for organ transplant, rejection prophylaxis, psoriasis, rheumatoid arthritis
Sandimmune
Sandimmune is used for organ transplant, rejection prophylaxis
Voclosporin
Voclosporin (brand name Lupkynis) is used to treat active lupus nephritis in adults with SLE ...
Tacrolimus
Tacrolimus is used for crohn's disease, graft versus host disease, nephrotic syndrome, organ ...
Cyclosporine
Cyclosporine is used for cogan's syndrome, crohn's disease, eczema, evan's syndrome, focal ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.