Comparing Prograf vs Rapamune
| Prograf | Rapamune |
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| Prograf (tacrolimus) | Rapamune (sirolimus) |
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Prescription only
Prescribed for Organ Transplant - Rejection Reversal, Organ Transplant - Rejection Prophylaxis. Prograf may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Lymphangioleiomyomatosis, Organ Transplant - Rejection Prophylaxis. Rapamune may also be used for purposes not listed in this medication guide. |
Related suggestions Organ Transplant, Rejection Prophylaxis
Popular comparisons
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| More about Prograf (tacrolimus) | More about Rapamune (sirolimus) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Prograf has an average rating of 8.1 out of 10 from a total of 28 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 8% reported a negative effect. |
Rapamune has an average rating of 9.5 out of 10 from a total of 3 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: Prograf side effects in more detail. |
See also: Rapamune side effects in more detail. |
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| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Prograf prices |
View all Rapamune prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other tacrolimus brands include: Astagraf XL, Envarsus XR |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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21.2 hours |
78 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 832 drugs are known to interact with Prograf:
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A total of 680 drugs are known to interact with Rapamune:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 08, 1994 |
September 15, 1999 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.