Comparing Semaglutide vs Zepbound
| Semaglutide | Zepbound (tirzepatide) |
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| Semaglutide | Zepbound (tirzepatide) |
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Prescription only
Semaglutide (Ozempic, Rybelsus) lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Obstructive Sleep Apnea/Hypopnea Syndrome. Zepbound may also be used for purposes not listed in this medication guide. |
Related suggestions Weight Loss (Obesity/Overweight)
Popular comparisons
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| More about Semaglutide | More about Zepbound (tirzepatide) | ||||||||
| Ratings & Reviews | |||||||||
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Semaglutide has an average rating of 6.9 out of 10 from a total of 2635 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 20% reported a negative effect. |
Zepbound has an average rating of 8.9 out of 10 from a total of 333 ratings on Drugs.com. 85% of reviewers reported a positive effect, while 1% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Semaglutide side effects |
View all Zepbound side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Zepbound prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Ozempic, Rybelsus, Wegovy | Other tirzepatide brands include: Mounjaro | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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168 hours |
120 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 273 drugs are known to interact with Semaglutide:
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A total of 414 drugs are known to interact with Zepbound:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 05, 2017 |
N/A |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Repatha
Repatha is used to lower high cholesterol alongside dietary changes and to reduce the risk of major ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Mounjaro
Mounjaro is used to treat type 2 diabetes in adults. It is a subcutaneous injection that can be ...
Jardiance
Jardiance (empagliflozin) is used to treat type 2 diabetes, chronic kidney disease and reduce the ...
Farxiga
Farxiga (dapagliflozin) is an oral prescription medication that may be given to certain adults with ...
Lasix
Lasix is a loop diuretic used to treat fluid retention from heart, liver, or kidney conditions, and ...
Xarelto
Xarelto (rivaroxaban) is a factor Xa inhibitor used to reduce the risk of blood clots and stroke in ...
Rybelsus
Rybelsus tablets are used to improve blood sugar control in adults with type 2 diabetes, and may ...
Zepbound
Zepbound (tirzepatide) is an FDA-approved weekly injection for weight loss and obstructive sleep ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.