Comparing Semaglutide vs Zepbound
| Semaglutide | Zepbound (tirzepatide) |
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| Semaglutide | Zepbound (tirzepatide) |
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Prescription only
Semaglutide (Ozempic, Rybelsus) lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Obstructive Sleep Apnea/Hypopnea Syndrome. Zepbound may also be used for purposes not listed in this medication guide. |
Related suggestions Weight Loss (Obesity/Overweight)
Popular comparisons
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| More about Semaglutide | More about Zepbound (tirzepatide) | ||||||||
| Ratings & Reviews | |||||||||
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Semaglutide has an average rating of 6.9 out of 10 from a total of 2595 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 21% reported a negative effect. |
Zepbound has an average rating of 8.9 out of 10 from a total of 305 ratings on Drugs.com. 86% of reviewers reported a positive effect, while 1% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Semaglutide side effects |
View all Zepbound side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Zepbound prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Ozempic, Rybelsus, Wegovy | Other tirzepatide brands include: Mounjaro | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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168 hours |
120 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 273 drugs are known to interact with Semaglutide:
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A total of 414 drugs are known to interact with Zepbound:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 05, 2017 |
N/A |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.