Comparing Rexulti vs Trintellix

For Major Depressive Disorder I've just started the starter pack of Rexulti I am on day 3. It is replacing Ability in my meds. I feel a lift in the depression, however I am experiencing some agitation and anxiety. I'm hoping this improves. It is affecting my dreaming...they aren't nightmares, just very vivid and strange. I am hopeful for this medicine if we can just get the agitation to cease.

For Major Depressive Disorder Mixed bag. On the positive side, it can pull you out of a dark hole really quick. On the negative, I'm starting to suspect it is causing a lot of my anger and irritation symptoms to go off the charts. I'm going to try going off of it for a few days again and if that makes me feel better, time to call my doc for something else.

For Depression Just a reminder for anyone taking the drug and reading these reviews, it take's at least a week or two before one can begin to feel the beneficial results. As for my personal experience; I'm one week on the drug, and I'm taking Ativan as well to treat MDD and anxiety disorders. Other than some rather uncomfortable nausea, and a day or two of vomiting, this has been a very beneficial experience. No weight gain, libido is intact, and I feel clear; however, I strongly recommend you not do any heavy drinking while on this drug, and if you have a history of heart burn or stomach ulcers, then it might be a good idea to use additional medication to treat any stomach problems. All in all, it's working for me =)

For Depression I've been on trintellix for 10 weeks now, roughly. I was on 5mg for awhile, now on ten. At first the nausea was unbearable and all it really did was stop me from getting overwhelmingly sad as often but now I've found that I'm more outgoing and capable of trying my best even in uncomfortable situations. The nausea is still there but it becomes super tolerable and gravol is a lifesaver. The only time it became a problem is when I was sick, I vomited non-stop, I had bronchitis so apparently the throat pain mixed with nausea was to blame. Still, overall trintellix has done wonders for my mental health and I'm hoping the majority of others can agree or find another medication that will do for you, what trintellix has done for me.