Comparing Premarin Vaginal vs Vagifem
| Premarin Vaginal (conjugated estrogens) | Vagifem (estradiol) |
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| Premarin Vaginal (conjugated estrogens) | Vagifem (estradiol) |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Postmenopausal Symptoms. Premarin Vaginal may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis. Vagifem may also be used for purposes not listed in this medication guide. |
Related suggestions Atrophic Vaginitis
Atrophic Urethritis
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| More about Premarin Vaginal (conjugated estrogens) | More about Vagifem (estradiol) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Premarin Vaginal has an average rating of 7.3 out of 10 from a total of 21 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 19% reported a negative effect. |
Vagifem has an average rating of 6.0 out of 10 from a total of 102 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Premarin Vaginal side effects |
View all Vagifem side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Premarin Vaginal prices |
View all Vagifem prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other estradiol brands include: Estrace Vaginal Cream, Estring, Imvexxy, Yuvafem | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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8 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 193 drugs are known to interact with Premarin Vaginal:
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A total of 244 drugs are known to interact with Vagifem:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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N/A |
March 26, 1999 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Premarin
Premarin is used to treat symptoms of menopause such as hot flashes, and vaginal dryness. Learn ...
Estrace
Estrace (estradiol) is used to treat symptoms of menopause such as hot flashes and vaginal dryness ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Lo Loestrin Fe
Lo Loestrin Fe (ethinyl estradiol and norethindrone acetate) birth control tablets are used to ...
Estradiol Patch
Estradiol Patch is used for atrophic urethritis, atrophic vaginitis, breast cancer, palliative ...
Vagifem
Vagifem vaginal inserts are used treat menopause symptoms such as dryness, burning, and irritation ...
Prempro
Prempro (conjugated estrogens and medroxyprogesterone) is used to treat the symptoms of menopause ...
Estrace Vaginal Cream
Estrace Vaginal Cream is used for atrophic urethritis, atrophic vaginitis
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.