Comparing Phentermine vs Zepbound
| Phentermine | Zepbound (tirzepatide) |
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| Phentermine | Zepbound (tirzepatide) |
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Prescription only
Phentermine may be used short-term as an aid to weight loss; however, it can be addictive and tolerance may develop to its weight-losing effects, rendering it less effective with time. Prescribed for... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Obstructive Sleep Apnea/Hypopnea Syndrome. Zepbound may also be used for purposes not listed in this medication guide. |
Related suggestions Weight Loss (Obesity/Overweight)
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| More about Phentermine | More about Zepbound (tirzepatide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Phentermine has an average rating of 8.6 out of 10 from a total of 3016 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 5% reported a negative effect. |
Zepbound has an average rating of 8.8 out of 10 from a total of 407 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 1% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Phentermine side effects |
View all Zepbound side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Phentermine prices |
View all Zepbound prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Adipex-P, Atti-Plex P, Lomaira | Other tirzepatide brands include: Mounjaro | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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20 hours |
120 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 196 drugs are known to interact with Phentermine:
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A total of 416 drugs are known to interact with Zepbound:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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August 14, 1973 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.