Penicillamine Alternatives Compared
| Penicillamine | Cuprimine (penicillamine) | Syprine (trientine) |
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| Penicillamine | Cuprimine (penicillamine) | Syprine (trientine) |
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Prescription only
Prescribed for Wilson's Disease, Cystinuria, Rheumatoid Arthritis. Penicillamine may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Wilson's Disease, Cystinuria, Rheumatoid Arthritis. Cuprimine may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Wilson's Disease. Syprine may also be used for purposes not listed in this medication guide. |
Related suggestions Wilson's Disease
Popular comparisons
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| More about Penicillamine | More about Cuprimine (penicillamine) | More about Syprine (trientine) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Penicillamine has an average rating of 9.0 out of 10 from a total of 2 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Cuprimine has an average rating of 10.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Syprine has an average rating of 10.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Penicillamine side effects |
View all Cuprimine side effects |
View all Syprine side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Penicillamine prices |
View all Cuprimine prices |
View all Syprine prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Cuprimine, D-Penamine, Depen, Depen Titratabs | Other penicillamine brands include: D-Penamine, Depen, Depen Titratabs | Other trientine brands include: Clovique, Cuvrior | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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3.2 hours |
3.2 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 123 drugs are known to interact with Penicillamine:
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A total of 123 drugs are known to interact with Cuprimine:
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A total of 46 drugs are known to interact with Syprine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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December 04, 1970 |
December 04, 1970 |
November 08, 1985 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.