Comparing Otezla vs Rinvoq LQ

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Otezla (apremilast)	Rinvoq LQ (upadacitinib)	Enter another drug to compare

Otezla (apremilast)

Rinvoq LQ (upadacitinib)

Prescription only

Otezla is a PDE4 inhibitor that may be used to treat adults with plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It may also be used to treat plaque psoriasis... View more

Prescription only

Prescribed for Polyarticular Juvenile Idiopathic Arthritis, Psoriatic Arthritis. Rinvoq LQ may also be used for purposes not listed in this medication guide.

More about Otezla (apremilast)

More about (upadacitinib)

Ratings & Reviews

Otezla has an average rating of 5.2 out of 10 from a total of 441 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 40% reported a negative effect.

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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Headaches (29.3%)
Nausea (25.4%)
Diarrhea (25.2%)
Depression (8.4%)
Upset stomach (7.7%)
Fatigue (5.4%)
Pain (5.0%)

View all Otezla side effects

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Drug Class

Antirheumatics

Antirheumatics

Generic Availability

Lower cost generic approved

No lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	55 tablet
Strength	10 mg-20 mg-30 mg
Per unit^*	$103.51
Cost^*	$5,693.16

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Quantity	180 mL
Strength	1 mg/mL
Per unit^*	$19.28
Cost^*	$3,470.21

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Dosage Forms

Oral tablet

Oral liquid

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

9 hours

14 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Drug Interactions

A total of 111 drugs are known to interact with Otezla:

15 major drug interactions (44 brand and generic names)
94 moderate drug interactions (251 brand and generic names)
2 minor drug interactions (4 brand and generic names)

A total of 613 drugs are known to interact with Rinvoq LQ:

380 major drug interactions (1254 brand and generic names)
223 moderate drug interactions (884 brand and generic names)
10 minor drug interactions (40 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Consumption of grapefruit, grapefruit juice, and supplements that contain grapefruit should be... View more

Disease Interactions

First Approval Date

March 21, 2014

N/A

WADA Class View classifications

N/A

More Information

Patient Resources

Otezla uses

N/A

Professional Resources

Prescribing information

N/A

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Otezla vs Rinvoq LQ

See also:

Stelara

Taltz

Skyrizi

Vtama

Humira

Rinvoq

Medrol

Decadron

Tremfya

Enbrel

Further information

Comparing Otezla vs Rinvoq LQ

See also:

Further information

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