Comparing Mestinon vs Midodrine
| Mestinon (pyridostigmine) | Midodrine |
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| Mestinon (pyridostigmine) | Midodrine |
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Prescription only
Prescribed for Myasthenia Gravis, Dysautonomia, Nerve Agent Pretreatment, Reversal of Nondepolarizing Muscle Relaxants. Mestinon may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Dysautonomia, Postural Orthostatic Tachycardia Syndrome, Hypotension. Midodrine may also be used for purposes not listed in this medication guide. |
Related suggestions Dysautonomia
Popular comparisons
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| More about Mestinon (pyridostigmine) | More about Midodrine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Mestinon has an average rating of 6.6 out of 10 from a total of 40 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 25% reported a negative effect. |
Midodrine has an average rating of 6.8 out of 10 from a total of 55 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 25% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Mestinon side effects |
View all Midodrine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Mestinon prices |
View all Midodrine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other pyridostigmine brands include: Mestinon Timespan, Regonol | Orvaten | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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N/A |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 102 drugs are known to interact with Mestinon:
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A total of 172 drugs are known to interact with Midodrine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 06, 1955 |
September 06, 1996 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.