Comparing Mestinon vs Midodrine
| Mestinon (pyridostigmine) | Midodrine |
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| Mestinon (pyridostigmine) | Midodrine |
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Prescription only
Prescribed for Myasthenia Gravis, Dysautonomia, Nerve Agent Pretreatment, Reversal of Nondepolarizing Muscle Relaxants. Mestinon may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Postural Orthostatic Tachycardia Syndrome, Dysautonomia, Hypotension. Midodrine may also be used for purposes not listed in this medication guide. |
Related suggestions Dysautonomia
Popular comparisons
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| More about Mestinon (pyridostigmine) | More about Midodrine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Mestinon has an average rating of 6.6 out of 10 from a total of 40 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 25% reported a negative effect. |
Midodrine has an average rating of 6.8 out of 10 from a total of 55 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 25% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Mestinon side effects |
View all Midodrine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Mestinon prices |
View all Midodrine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other pyridostigmine brands include: Mestinon Timespan, Regonol | Orvaten | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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N/A |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 100 drugs are known to interact with Mestinon:
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A total of 171 drugs are known to interact with Midodrine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 06, 1955 |
September 06, 1996 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.