Comparing Mestinon vs Midodrine
| Mestinon | Midodrine |
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| Mestinon (pyridostigmine) | Midodrine |
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Prescription only
Prescribed for Myasthenia Gravis, Dysautonomia, Reversal of Nondepolarizing Muscle Relaxants, Nerve Agent Pretreatment. Mestinon may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Postural Orthostatic Tachycardia Syndrome, Dysautonomia, Hypotension. midodrine may also be used for purposes not listed in this medication guide. |
Related suggestions Dysautonomia
Popular comparisons
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| More about Mestinon (pyridostigmine) | More about Midodrine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Mestinon has an average rating of 6.5 out of 10 from a total of 40 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 27% reported a negative effect. |
Midodrine has an average rating of 6.6 out of 10 from a total of 49 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 30% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: Mestinon side effects in more detail. |
See also: midodrine side effects in more detail. |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Mestinon prices |
View all midodrine prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other pyridostigmine brands include: Mestinon Timespan, Regonol | Orvaten | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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N/A |
4 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 77 drugs are known to interact with Mestinon:
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A total of 168 drugs are known to interact with midodrine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 06, 1955 |
September 06, 1996 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.