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Medications for Reversal of Nondepolarizing Muscle Relaxants

About Reversal of Nondepolarizing Muscle Relaxants:  A course of action taken to stop nondepolarizing muscle relaxants – a group of drugs that cause muscle relaxation by competitively blocking the binding of acetylcholine to its receptors.

Drugs Used for Reversal of Nondepolarizing Muscle Relaxants

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
pyridostigmine C N 1 review
1.0

Generic name: pyridostigmine systemic

Brand names:  Mestinon, Regonol, Mestinon Timespan

Drug class: cholinergic muscle stimulants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

neostigmine C N Add review
9.0

Generic name: neostigmine systemic

Drug class: cholinergic muscle stimulants, miscellaneous genitourinary tract agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Mestinon C N 1 review
1.0

Generic name: pyridostigmine systemic

Drug class: cholinergic muscle stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

sugammadex N N Add review
0.0

Generic name: sugammadex systemic

Brand name:  Bridion

Drug class: miscellaneous central nervous system agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Regonol C N Add review
0.0

Generic name: pyridostigmine systemic

Drug class: cholinergic muscle stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

atropine / edrophonium C N X Add review
0.0

Generic name: atropine / edrophonium systemic

Drug class: cholinergic muscle stimulants

For consumers: interactions,

For professionals: A-Z Drug Facts

Mestinon Timespan C N Add review
0.0

Generic name: pyridostigmine systemic

Drug class: cholinergic muscle stimulants

For consumers: dosage, interactions, side effects

Bridion N N Add review
0.0

Generic name: sugammadex systemic

Drug class: miscellaneous central nervous system agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

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