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Generic name: sugammadexsoo-GAM-ma-dex ]
Drug class: Miscellaneous central nervous system agents

Medically reviewed by on Apr 17, 2023. Written by Cerner Multum.

What is Bridion?

Bridion reverses the effects of certain medications that are given during surgical procedures to relax your muscles.

Bridion is used at the end of surgery, to help restore muscle function that has been blocked during surgery by the other medicines.

Bridion may also be used for purposes not listed in this medication guide.

Bridion side effects

Get emergency medical help if you have signs of an allergic reaction: hives, skin rash or redness; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • flushing (warmth, redness, or tingly feeling);

  • itching;

  • eye pain, itching, or discomfort; or

  • extreme weakness, weak or shallow breathing.

Common side effects of Bridion may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Before you receive Bridion, tell your doctor about all your medical conditions or allergies, and all the medicines you are using. Also make sure your doctor knows if you are pregnant or breast-feeding.

Before taking this medicine

You should not use Bridion if you are allergic to it.

To make sure Bridion is safe for you, tell your doctor if you have:

  • kidney disease (or if you are on dialysis);

  • liver disease;

  • a bleeding or blood clotting disorder such as hemophilia;

  • low levels of platelets in blood; or

  • a breathing disorder.

It is not known whether Bridion will harm an unborn baby. Tell your doctor if you are pregnant.

Bridion can make hormonal birth control less effective. For at least 7 days after you receive this medicine, use a non-hormonal back-up birth control (condom or diaphragm with spermicide) to prevent pregnancy. Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during this time.

It is not known whether sugammadex passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How is Bridion given?

Bridion is injected into a vein through an IV. A healthcare provider will give you this medicine in a single injection.

Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are receiving Bridion.

What happens if I miss a dose?

Since Bridion is used as a single dose, it does not have a daily dosing schedule.

What happens if I overdose?

Since Bridion is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving Bridion?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect Bridion?

Tell your doctor about all your current medicines, especially:

Other drugs may interact with sugammadex, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.