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Sugammadex use while Breastfeeding

Drugs containing Sugammadex: Bridion

Medically reviewed by Drugs.com. Last updated on Feb 7, 2021.

Sugammadex Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the clinical use of sugammadex during breastfeeding. Because sugammadex is a large, highly polar molecule with a molecular weight of 2002 Da., the amount in milk is likely to be very low and oral absorption by the infant is unlikely. Sugammadex is acceptable to use during breastfeeding.[1,2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Neostigmine

References

1.
Schaller SJ, Fink H. Sugammadex as a reversal agent for neuromuscular block: An evidence-based review. Core Evid. 2013;8:57–67. [PMC free article: PMC3789633] [PubMed: 24098155]
2.
Richardson MG, Raymond BL. Sugammadex administration in pregnant women and in women of reproductive potential: A narrative review. Anesth Analg. 2020;130:1628–37. [PubMed: 31283616]

Substance Identification

Substance Name

Sugammadex

CAS Registry Number

343306-71-8

Drug Class

Breast Feeding

Lactation

Antidotes

Gamma-Cyclodextrins

Neuromuscular Blockade

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Further information

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