Harvoni Alternatives Compared
| Harvoni | Epclusa | Sovaldi |
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| Harvoni (ledipasvir / sofosbuvir) | Epclusa (sofosbuvir / velpatasvir) | Sovaldi (sofosbuvir) |
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Prescription only
Harvoni is a combination tablet containing ledipasvir and sofosbuvir. It may be used to treat certain genotypes of the hepatitis C virus in adults and children over the age of three. It is usually... View more |
Prescription only
Epclusa is a combination tablet containing velpatasvir and sofosbuvir. It may be used to treat all six genotypes of the hepatitis C virus in adults and children over the age of three. It is usually... View more |
Prescription only
Sovaldi may be used to treat certain genotypes of the hepatitis C virus in adults and children over the age of three. It must be given in combination with other treatments and cannot be used alone to... View more |
Related suggestions |
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| More about Harvoni (ledipasvir / sofosbuvir) | More about Epclusa (sofosbuvir / velpatasvir) | More about Sovaldi (sofosbuvir) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Harvoni has an average rating of 8.6 out of 10 from a total of 397 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 10% reported a negative effect. |
Epclusa has an average rating of 7.7 out of 10 from a total of 369 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 13% reported a negative effect. |
Sovaldi has an average rating of 7.7 out of 10 from a total of 47 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: Harvoni side effects in more detail. |
See also: Epclusa side effects in more detail. |
See also: Sovaldi side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Harvoni prices and generic prices |
View all Epclusa prices and generic prices |
View all Sovaldi prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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47 hours |
27 hours |
27 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category B
No proven risk in humans
Category X
Not for use in pregnancy
In Combination With Ribavirin Or Peginterferon Alfa/Ribavirin See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 172 drugs are known to interact with Harvoni:
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A total of 184 drugs are known to interact with Epclusa:
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A total of 81 drugs are known to interact with Sovaldi:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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October 10, 2014 |
June 28, 2016 |
December 06, 2013 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.