Harvoni (ledipasvir / sofosbuvir) Drug Interactions
A total of 95 drugs are known to interact with Harvoni (ledipasvir / sofosbuvir).
- 19 major drug interactions
- 72 moderate drug interactions
- 4 minor drug interactions
Check for interactions
Most frequently checked interactions
View interaction reports for Harvoni (ledipasvir / sofosbuvir) and the medicines listed below.
- Advil (ibuprofen)
- Aleve (naproxen)
- amlodipine
- amoxicillin
- Benadryl (diphenhydramine)
- clonazepam
- gabapentin
- hydrochlorothiazide
- ibuprofen
- Klonopin (clonazepam)
- levothyroxine
- lisinopril
- melatonin
- metformin
- methadone
- metoprolol
- omeprazole
- oxycodone
- ranitidine
- ribavirin
- spironolactone
- Suboxone (buprenorphine / naloxone)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Viagra (sildenafil)
- Vitamin D3 (cholecalciferol)
- Vitamins (multivitamin)
- Xanax (alprazolam)
Harvoni (ledipasvir / sofosbuvir) disease interactions
There is 1 disease interaction with Harvoni (ledipasvir / sofosbuvir):
More about Harvoni (ledipasvir / sofosbuvir)
- Side Effects
- During Pregnancy
- Dosage Information
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- Compare Alternatives
- Support Group
- Pricing & Coupons
- En Español
- 370 Reviews
- Drug class: antiviral combinations
- FDA Alerts (2)
- FDA Approval History
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
