Harvoni (ledipasvir / sofosbuvir) Drug Interactions
A total of 177 drugs (770 brand and generic names) are known to interact with Harvoni (ledipasvir / sofosbuvir).
- 31 major drug interactions (119 brand and generic names)
- 142 moderate drug interactions (643 brand and generic names)
- 4 minor drug interactions (8 brand and generic names)
Common medications checked in combination with Harvoni (ledipasvir / sofosbuvir)
- Advil (ibuprofen)
- Aleve (naproxen)
- amlodipine
- amoxicillin
- Benadryl (diphenhydramine)
- clonazepam
- gabapentin
- hydrochlorothiazide
- ibuprofen
- Klonopin (clonazepam)
- levothyroxine
- lisinopril
- losartan
- melatonin
- metformin
- methadone
- milk thistle
- omeprazole
- oxycodone
- ranitidine
- ribavirin
- spironolactone
- Suboxone (buprenorphine / naloxone)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Viagra (sildenafil)
- Vitamin D3 (cholecalciferol)
- Vitamins (multivitamin)
- Xanax (alprazolam)
Check for interactions with Harvoni (ledipasvir / sofosbuvir)
See Also
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
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