Harvoni Interactions
There are 178 drugs known to interact with Harvoni (ledipasvir/sofosbuvir), along with 4 disease interactions. Of the total drug interactions, 24 are major, 148 are moderate, and 6 are minor.
- View all 178 medications that may interact with Harvoni
- View Harvoni disease interactions (4)
Most frequently checked interactions
View interaction reports for Harvoni (ledipasvir / sofosbuvir) and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- amlodipine
- bupropion
- clonazepam
- furosemide
- gabapentin
- hydrochlorothiazide
- hydroxyzine
- Klonopin (clonazepam)
- levothyroxine
- lisinopril
- losartan
- melatonin
- metformin
- methadone
- metoprolol
- milk thistle
- omeprazole
- oxycodone
- pantoprazole
- prednisone
- ranitidine
- ribavirin
- spironolactone
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
Harvoni disease interactions
There are 4 disease interactions with Harvoni (ledipasvir / sofosbuvir) which include:
Report options
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- Reviews (403)
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- Side effects
- Dosage information
- Patient tips
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- FDA approval history
- Drug class: antiviral combinations
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
