Harvoni (ledipasvir / sofosbuvir) Drug Interactions
A total of 161 drugs (734 brand and generic names) are known to interact with Harvoni (ledipasvir / sofosbuvir).
- 29 major drug interactions (115 brand and generic names)
- 128 moderate drug interactions (611 brand and generic names)
- 4 minor drug interactions (8 brand and generic names)
Check for interactions with Harvoni (ledipasvir / sofosbuvir)
Common medications checked in combination with Harvoni (ledipasvir / sofosbuvir)
- amlodipine
- clonazepam
- gabapentin
- hydrochlorothiazide
- Klonopin (clonazepam)
- levothyroxine
- lisinopril
- metformin
- methadone
- milk thistle
- omeprazole
- oxycodone
- ranitidine
- ribavirin
- spironolactone
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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