Comparing Epclusa vs Harvoni
| Epclusa (sofosbuvir / velpatasvir) | Harvoni (ledipasvir / sofosbuvir) |
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| Epclusa (sofosbuvir / velpatasvir) | Harvoni (ledipasvir / sofosbuvir) |
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Prescription only
Epclusa is used to treat adults and children 3 years and older with chronic HCV genotype 1, 2, 3, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis. For decompensated cirrhosis it... View more |
Prescription only
Harvoni is a combination tablet containing ledipasvir and sofosbuvir. It may be used to treat certain genotypes of the hepatitis C virus in adults and children over the age of three. It is usually... View more |
Related suggestions Hepatitis C
Popular comparisons
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| More about Epclusa (sofosbuvir / velpatasvir) | More about Harvoni (ledipasvir / sofosbuvir) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Epclusa has an average rating of 7.6 out of 10 from a total of 407 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 12% reported a negative effect. |
Harvoni has an average rating of 8.4 out of 10 from a total of 403 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 11% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Epclusa side effects |
View all Harvoni side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Epclusa prices |
View all Harvoni prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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27 hours |
47 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 203 drugs are known to interact with Epclusa:
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A total of 179 drugs are known to interact with Harvoni:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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June 28, 2016 |
October 10, 2014 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.