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Epclusa Interactions

There are 197 drugs known to interact with Epclusa (sofosbuvir/velpatasvir), along with 3 disease interactions. Of the total drug interactions, 46 are major, 145 are moderate, and 6 are minor.

Does Epclusa interact with my other drugs?

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Most frequently checked interactions

View interaction reports for Epclusa (sofosbuvir / velpatasvir) and the medicines listed below.

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Epclusa disease interactions

There are 3 disease interactions with Epclusa (sofosbuvir / velpatasvir) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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