Purine nucleosides

What are Purine nucleosides

Purine nucleosides are antiviral agents that have selective activity against herpes simplex virus types 1 (cold sores) and 2 (genital herpes) and varicella zoster virus (chicken pox).

The purine nucleoside molecule is converted to a monophosphate by viral thymidine kinases. The monophosphate is then converted to diphosphate and then into a triphosphate form by cellular enzymes. The triphosphate form blocks the replication of viral DNA by inhibiting viral DNA polymerase and terminating the growing viral DNA chain.

Purine nucleosides are more potent against the viral enzymes than the host enzymes.

List of Purine nucleosides:

Drug Name ( View by: Brand | Generic )	Reviews	Ratings
Ribasphere (Pro, More...) generic name: ribavirin	1 review		10
Valtrex (Pro, More...) generic name: valacyclovir	216 reviews		9.1
Famvir (Pro, More...) generic name: famciclovir	13 reviews		8.7
Sitavig (Pro, More...) generic name: acyclovir	8 reviews		8.6
Zovirax (Pro, More...) generic name: acyclovir	13 reviews		8.5
Copegus (Pro, More...) generic name: ribavirin	1 review		8.0
Moderiba (Pro, More...) generic name: ribavirin	1 review		8.0
Valcyte (Pro, More...) generic name: valganciclovir	1 review		8.0
Rebetol (Pro, More...) generic name: ribavirin	2 reviews		5.5
RibaPak (More...) generic name: ribavirin	0 reviews		1.0
Cytovene (Pro, More...) generic name: ganciclovir	0 reviews		0.0
RibaTab (More...) generic name: ribavirin	0 reviews		0.0
Virazole (Pro, More...) generic name: ribavirin	0 reviews		0.0
Vistide (Pro, More...) generic name: cidofovir	0 reviews		0.0