Comparing Harvoni vs Zepatier
| Harvoni (ledipasvir / sofosbuvir) | Zepatier (elbasvir / grazoprevir) |
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| Harvoni (ledipasvir / sofosbuvir) | Zepatier (elbasvir / grazoprevir) |
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Prescription only
Harvoni is a combination tablet containing ledipasvir and sofosbuvir. It may be used to treat certain genotypes of the hepatitis C virus in adults and children over the age of three. It is usually... View more |
Prescription only
Prescribed for Hepatitis C. Zepatier may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Harvoni (ledipasvir / sofosbuvir) | More about Zepatier (elbasvir / grazoprevir) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Harvoni has an average rating of 8.6 out of 10 from a total of 403 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 10% reported a negative effect. |
Zepatier has an average rating of 8.9 out of 10 from a total of 53 ratings on Drugs.com. 84% of reviewers reported a positive effect, while 5% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Harvoni side effects |
View all Zepatier side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Harvoni prices |
View all Zepatier prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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47 hours |
31 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 177 drugs are known to interact with Harvoni:
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A total of 238 drugs are known to interact with Zepatier:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 10, 2014 |
January 28, 2016 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.