Folic acid Alternatives Compared
Folic acid | Deplin | L-methylfolate |
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Folic acid | Deplin (l-methylfolate) | L-methylfolate |
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Prescription and OTC
Folic acid is the synthetic form of folate (also called vitamin B9) which is necessary for proper growth and development and several other vital bodily processes. All women of childbearing age should... View more |
Prescription only
Prescribed for Folate Deficiency, Hyperhomocysteinemia, Depression. Deplin may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Prescribed for Folate Deficiency, Hyperhomocysteinemia, Depression, Borderline Personality Disorder. l-methylfolate may also be used for purposes not listed in this medication guide. |
Related suggestions Folate Deficiency
Popular comparisons
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More about Folic acid | More about Deplin (l-methylfolate) | More about L-methylfolate | ||||||||
Ratings & Reviews | ||||||||||
Folic acid has an average rating of 5.3 out of 10 from a total of 9 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 29% reported a negative effect. |
Deplin has an average rating of 7.7 out of 10 from a total of 114 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 16% reported a negative effect. |
L-methylfolate has an average rating of 7.8 out of 10 from a total of 165 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 16% reported a negative effect. |
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Drug Class | ||||||||||
Side Effects | ||||||||||
See also: folic acid side effects in more detail. |
See also: Deplin side effects in more detail. |
See also: l-methylfolate side effects in more detail. |
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Generic Availability | ||||||||||
Lower cost generic |
N/A |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||
View all folic acid prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Forms Available | ||||||||||
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Brand Names | ||||||||||
FA-8, FaLessa, Folacin-800, Folvite | Other l-methylfolate brands include: Denovo, Duleek-DP, Elfolate, L-Methylfolate Forte, XaQuil XR | Denovo, Deplin, Duleek-DP, Elfolate, L-Methylfolate Forte, XaQuil XR | ||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||
N/A |
N/A |
N/A |
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CSA Schedule ** View glossary of terms | ||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||
Category A
Studies show no risk
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||
A total of 35 drugs are known to interact with folic acid:
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A total of 25 drugs are known to interact with Deplin:
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A total of 25 drugs are known to interact with l-methylfolate:
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Alcohol/Food/Lifestyle Interactions | ||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||
First Approval Date | ||||||||||
June 02, 1947 |
N/A |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||
Patient resources | ||||||||||
Professional Resources | ||||||||||
N/A |
N/A |
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Related Treatment Guide | ||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.