Fluorouracil topical Alternatives Compared
| Fluorouracil topical | Efudex (fluorouracil) | Tolak (fluorouracil) |
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| Fluorouracil topical | Efudex (fluorouracil) | Tolak (fluorouracil) |
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Prescription only
Prescribed for Actinic Keratosis, Basal Cell Carcinoma, Warts, Skin Cancer, Keratosis. Fluorouracil topical may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Actinic Keratosis, Basal Cell Carcinoma, Skin Cancer, Keratosis. Efudex may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Actinic Keratosis, Keratosis. Tolak may also be used for purposes not listed in this medication guide. |
Related suggestions Keratosis
Actinic Keratosis
Popular comparisons
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| More about Fluorouracil topical | More about Efudex (fluorouracil) | More about Tolak (fluorouracil) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Fluorouracil topical has an average rating of 7.4 out of 10 from a total of 311 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 15% reported a negative effect. |
Efudex has an average rating of 7.4 out of 10 from a total of 127 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 14% reported a negative effect. |
Tolak has an average rating of 6.4 out of 10 from a total of 26 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Fluorouracil topical side effects |
View all Efudex side effects |
View all Tolak side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all Fluorouracil topical prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Tolak prices |
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| Dosage Forms | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| Carac, Efudex, Efudex Occlusion Pack, Fluoroplex, Tolak | Other fluorouracil brands include: Carac, Efudex Occlusion Pack, Fluoroplex, Tolak | Other fluorouracil brands include: Carac, Efudex, Efudex Occlusion Pack, Fluoroplex | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 6 drugs are known to interact with Fluorouracil topical:
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A total of 6 drugs are known to interact with Efudex:
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A total of 6 drugs are known to interact with Tolak:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||
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July 29, 1970 |
July 29, 1970 |
September 18, 2015 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient Resources | ||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.