Comparing Epiduo vs Retin-A
| Epiduo (adapalene / benzoyl peroxide) | Retin-A (tretinoin) |
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| Epiduo (adapalene / benzoyl peroxide) | Retin-A (tretinoin) |
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Prescription only
Prescribed for Acne. Epiduo may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Photoaging of the Skin, Lichen Sclerosus, Acne, Necrobiosis Lipoidica Diabeticorum. Retin-A may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Epiduo (adapalene / benzoyl peroxide) | More about Retin-A (tretinoin) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Epiduo has an average rating of 7.3 out of 10 from a total of 726 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 17% reported a negative effect. |
Retin-A has an average rating of 7.9 out of 10 from a total of 97 ratings on Drugs.com. 77% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Epiduo side effects |
View all Retin-A side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Epiduo prices |
View all Retin-A prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other adapalene / benzoyl peroxide brands include: Epiduo Forte | Other tretinoin brands include: Altinac, Altreno, Atralin, Avita, Obagi, Refissa, Renova, Retin A Micro, Retin-A and Renova View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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51 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 17 drugs are known to interact with Epiduo:
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A total of 12 drugs are known to interact with Retin-A:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 08, 2008 |
October 20, 1971 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.