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User Reviews for Epiduo

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671 reviews 524 medications

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Epiduo

Tin · Taken for less than 1 month April 22, 2021

For Acne: “Everyone here is like, "ONLY USE PEA-SIZED AMOUNT or it will burn and begin to irritate your skin, don't worry it'll still work." Then there was me before I read these reviews crying because I used it as a moisturizer and my skin feels like it's burning."”

5 / 10
Sam · Taken for less than 1 month April 21, 2021

For Acne: “My son is currently using Epiduo gel and lymacycline, he is 4 weeks in and his face is really red, not as bad as it was, but still red which at 17 is causing him some embarrassment at college . I bought him some aloe Vera cooling get from Holland Barrett about a week ago which slowly seems to be helping the redness go down and he said his skin doesn’t hurt since using it l”

beanie April 21, 2021

For Acne: “I've been on Epiduo for 14 weeks. I'm 18 and have had a lot of trouble with acne for the past 5 years, mainly on my jaw, chin and forehead which all big, deep pimples. Now, this is not a miracle cream, but it has helped my skin so, so, much. The first week was fine, apart from a little dryness. But weeks 2-4 were pretty brutal, I had a very intense purging stage and my skin was very dry. After that, my skin has slowly improved to the point where I only have 1 or 2 active pimples at a time compared to 15-20 before hand. So, my advice would be to prepare for your skin to get worse before it gets better. Also, listen to your skin, it's okay to take nights off to recover, as well as only using a pea sized amount so your skin doesn't get too dry. I now use it 4-5 times a week and my skin has been pretty consistent. I think this is a great option and suggest you try it! Good luck and know that it gets better -- just power through that purging stage!”

9 / 10
Anonymous · Taken for less than 1 month February 4, 2021

For Acne: “So I have been battling acne for ages, I am currently on lymecycline as well as Epiduo. I'm only about a week into using Epiduo but I am in so much pain I'm thinking of using it less. My face is so red, dry and it burns whenever I put anything on my skin (eg. face wash and moisturizer), not just the treatment. Is this normal? I have no idea, I have used Duac in the passed which actually has more benzoyl peroxide in it so I don't know why my skin is reacting so badly to Epiduo. Anyway, I can't say anything about its effectiveness to treat acne because I haven't been using it long enough. So I'll let you know how it goes.”

clearedmerightup! · Taken for 2 to 5 years May 1, 2020

For Acne: “Used Epiduoyears ago after coming off of oral contraceptives. Worked very well and I didn't have to use it for a few years afterwards. Recently, I'm having hormonal breakouts again around my chin and cheekbones, so I got another prescription. Works like a charm! PLEASE NOTE: moisturize first, let the moisturizer completely dry (to avoid the cream being absorbed too rapidly into the skin), and then apply the TINIEST amount to the affected areas and spread it thin. AVOID your eyes or anywhere even near your eyes! DO NOT use it everyday when you first start using it! ONLY use it once a day! Using it more frequently will not improve your results! You have to build a tolerance or your face will burn like fire! If it starts to burn, then give yourself a day or 2 break before trying again. Hope this helps.”

10 / 10
Sybil May 3, 2020

For Acne: “This is my third week of epiduo. All my life I’ve had beautiful skin. Until I turned 28 and had horrible hormonal acne on my cheeks and jawline. The acne is a combination of blackheads, cysts, comedones, white heads and IT IS PAINFUL. My skin is oily too! I just look at my face and want to cry. My doctor prescribed epiduo and Dermaplex soap free face scrub and the first week burnt like anything. My skin felt like it was on fire and I was told to use an SPF moisturizer along with it burnt as soon as I applied anything, the itchiness was irritating too but I pushed through. I’m on my third week and I still have these hard bumps under my skin and whiteheads that seem to come overnight but I’m being patient as I heard that it takes about 2 months to see real results. I want to avoid any oral treatment for my acne as I’m trying to have a baby and meds like accutane are said to cause severe birth defects. I will give an update in a few weeks about the epiduo and the baby. Wish me luck!”

5 / 10
evensteven · Taken for 1 to 6 months January 25, 2021

For Acne: “This is my second time on Epiduo. The first time, a couple years ago, I was on it for 3 months before I got fed up of my skin purging and continually getting way way worse. I thought 3 months was a long time to still be purging so I just gave up. DO NOT give up! I wish I hadn't, having read many reviews here and elsewhere stating that it may take 4-6 months for purging to end and for skin to clear. I have now decided to give it another go for a FULL 6 MONTHS. I am currently 3 months in and, again, my skin is so much worse than when I started it, constantly dry, red and full of hyperpigmentation. I am so self-conscious of how bad it's got, but I will keep pushing through to mid-April and see whether it delivers. I will update then. Please keep persisting however bad it gets, it has to get bad before it improves!”

5 / 10
Hayes August 26, 2020

For Acne: “I’ve been using Epiduo since January 24th, 2020. My advice is stay strong for the first few months. Don’t expect any results for 3-5 months and expect your skin to look horribly worse. Stay strong during that period. After 3-5 months, the face should look horribly red but breakouts should be getting to a minimum. For the next few months, epiduo should be still in use for the redness and scars. This takes 3 months for the redness to be only visible really up close. I would recommend this gel but you must not expect to have clear smooth skin in the first 2 months definitely. If lucky 3-4 months but should make sure to know that 8 months could be a possibility and prepare and trust the process. My skin still isn’t where I want it so I will still be using this to get the scaring fade but compared to a few months ago my skin looks 10x better.”

8 / 10
Mea1990 August 22, 2014

For Acne: “Its funny to read how many get "burned and dry/ flaky skin". The first thing my doctor told me was, EASE into it! use a VERY light layer and ONLY at night - not in the morning as well. A pea sized amount is enough. Put it on your finger and dot it around your face and then massage them out. He also told me that if it starts to burn/hurt, STOP using it for a few days. You should NEVER EVER keep using it when your face is in pain, obviously. Plus you need a very good, heavy moisturiser. This stuff is made from peroxide and retinoid, so it will sting a little the first times you use it, but if you use common sense it will go away within weeks. I feel bad that people use it the wrong way and then blame the product. Works great for me”

9 / 10
Liz · Taken for 6 months to 1 year June 8, 2020

For Acne: “I have had acne my whole life. It started to get extremely bad when my Dr. put me on birth control for hormone therapy. At first I didn't really think the Epiduo cream was working because it made my face worse for 2 good months. My neck would itch extremely bad and when I would work out it would turn bright red. I had read some reviews that said DON'T GIVE UP!! It took a good 6 months for my face to clear but it was so worth it!! This medicine does take time to work but I promise you will feel so much better in the end! Stick with it and you will see results!”

10 / 10
acnejourneyx · Taken for 1 to 6 months January 23, 2020

For Acne: “My doctor prescribed me epiduo around 7 weeks ago and I have been using it ever since. I have experienced the burning sensation throughout the process so far, however it is not major. I've had mild peeling/dry skin, the area that's been the most dry are my eyelids - but I have been using cetaphil moisturiser to help with this. I definitely had a bad purging stage within the first 4 weeks, which then subsided. However, I am still purging around my chin quite badly (large lumps under the skin), and I really hope that this subsides as I have heard that perseverance is key and that it may take up to 3 months to improve. Is anyone else still experiencing purging at week 7?”

5 / 10
Abi · Taken for less than 1 month February 19, 2020

For Acne: “I've only being using it for 5 days but the first 2 days it was fine but I have now developed a burning sensation leaving red mark's on my cheeks and making the skin around my cheeks, nose and mouth really dry and flaky”

5 / 10
Jess October 25, 2020

For Acne: “The very first week of using it I felt like my acne had pretty much disappeared, and then the purge started. It got worse over the first 4-5 months. I had horrendous cystic acne even worse than when I had started. My doctor told me to give it another few months so I stuck at it. I had horrendously dry skin alongside the purge and no makeup would cover my skin. Was it worth it as not my skin has never been clearer in all my life. I had to really stick with it to see the results I've seen today. This is a MIRACLE drug. I also use La Roche Posay cleanser for medicated skin and all the Vitamin E skincare range from Superdrug, alongside a rose water toner. I make sure to keep on top of my skincare routine daily, on top of using the Epiduo cream at night. PUT A PEA SIZED AMOUNT ON AT THE START. It will burn for the first 8 weeks. No photos do it justice. I look in the mirror and I am no longer ashamed at my skin 7 months later. This drug has been my saviour!☆☆☆☆☆”

10 / 10
bébé January 19, 2021

For Acne: “I have been using Epiduo for 17 nights. Initially it made my skin super smooth, no breakouts, burning or purging. However after about a week it became extremely painful and my skin burned like crazy. Dry patches appeared around my eyes and mouth. I moisturised with Bria Organic Balm and it cleared up within 2-4 days. One thing I will say for those who experience dry patches, burning and peeling is to protect them whilst they heal. Put on a thin layer of thick moisturiser and massage into the affected area and cover it with Vaseline. Vaseline acts as a barrier and therefore the benzoyl peroxide won’t travel to the affected areas. Vaseline is your friend in the fight against burning. Also a handheld fan - or really any fan - is the best to just point at your face and sleep with! When they say a pea sized amount, they mean it. You want as little as possible, but don’t worry it will still work.”

8 / 10
Laura April 7, 2021

For Acne: “I started Epiduo early December 2020 for my moderate/severe acne so it’s been about 4 months now. I started because I suffered from mostly closed comedones and had super textured skin. Even if there were no red pimples my skin would look really bumpy in certain lighting and it made makeup look nasty. I was told to use it every other night for 2 weeks then use it every night. I think I ignored my doctor (don’t do that) and just stared using it every night right off the bat. It did make my skin super red and flaky for a bit so get a good moisturizer (I use CeraVe moisturizing cream). It made my skin a lot worse in the first month and a half, but at 3 months my skin was pretty much clear, just a few scars remaining. At this point my skin is clear (I’ve never as clear skin so woohoo!). My skin is starting to get really dry again so I’m gonna start using it every other day again and see how that works. Just stay patient with it,”

10 / 10
wenz · Taken for 1 to 6 months January 1, 2020

For Acne: “This Epiduo was a miracle cream! Coupled with antibiotics, it completely cured my acne and clogged pores. The first 2-3 months was absolutely terrible. So i urge all of you to not give up on the treatment. The clogged pores started to become pimples and I had to squeeze all of them out. Things got better after the 4 month and now I'm into my 5 month with no clogged pores or pimples at all!!!!! So guys if you are using this for the first 2-3 months and are experiencing a purge, please DO NOT give up on it. Keep persevering and you'll see the light. I used the gel every night and it made my face red and itchy but I continued on and eventually when things got better I cut down to applying it once every two days.”

9 / 10
Mum of tween · Taken for less than 1 month August 22, 2020

For Acne: “A dermatologist prescribed this for my tween son who had blackheads on his nose, I had tried a number of over the counter products that if anything just made it worse. So I made an appointment with the dermatologist for him and he prescribed Epiduo. He told us on the first day put it on for an hour and wash off half an hour later put on Cetaphill Moisturiser, The 2nd day two hours, the 3rd day 3 hours Etc and then after 5 days leaving it on over night, still putting the moisturiser on half an hour after. We have had no dryness or irritation, the Epiduo seemed to bring any congestion in the skin up in tiny bumps and after 3 weeks his skin is clear from nearly blemishes. Don’t be afraid for It to bring a spot out this means it’s working, stick with it and be consistent.”

10 / 10
Cruz · Taken for 1 to 6 months June 2, 2020

For Acne: “Epiduo has honestly been the only product which has had a significant impact on my skin. My acne got much worse on epiduo for a couple of months (worse than ever before), but I stuck with it and now five months into treatment, my acne has completely gone. Only minor scars remain from the intense period which are getting less notable by the day. I definitely recommend anyone suffering with moderate acne to try it!”

10 / 10
Zoe · Taken for 1 to 6 months November 4, 2020

For Acne: “Hello!!! I started using Epiduo in mid-July and 3-months later I'm still getting significant breakouts (small whiteheads and cystic) and blackheads. I've been reading that the cream can take up to 3-5 months to be effective, so I'm holding out hope. The areas that weren't congested pre-epiduo are SUPER smooth and clear (forehead and nose); however, my cheeks are still very congested. I have also developed lots of red marks from pigmentation. With all my strength I have pushed out the purge for this long...I will keep going.”

8 / 10
Mary January 15, 2021

For Acne: “I started using Epiduo in November 2019 and back then my skin wasn’t very good. I had mild/moderate acne at the time and started using epiduo once, maybe twice a day. The first month was horrible and my skin started to get way worse. My breakouts were way worse than when I started. I didn’t have a burning sensation however my face started peeling like crazy. I had to use moisturizer all the time and makeup would never cover it up. At the 2-3 month mark my skin started getting slightly better with pretty bad scarring. However, when I reached the 6 month mark of this medication I was VERY pleased with the results. It got rid of my scarring drastically and my breakouts now are a lot better than they were before. I still have acne here and there but nothing compared to what it was before. It doesn’t work for everybody but it worked miracles on my skin.”

9 / 10
Lea · Taken for 1 to 6 months January 1, 2020

For Acne: “Do not give up!! I was about to stop my treatment but I'm glad I kept going. It is week 10 for me and it just started to clearing up. I had a bad, massive break out at week 9 and seriously thought it wasn't working for me. And now it's finally getting better. So do not give up, even if it seems it's not working I promise it will, just be patient.:)”

9 / 10
Cookie February 11, 2020

For Acne: “Been using epiduo 0.1 gel for around 2 month, the first few days after using my skin was on fire but I carried on the next night and from then on and it never happened again. The doctor did tell me I would get this burn so I knew it was normally and not a reaction. I am super pleased with the results I've not had huge bumps or spots and if I have got a pimple within the day it’s gone it doesn’t progress in to a huge angry looking lump. If your just starting using this gel keep going the results are amazing.”

10 / 10
May · Taken for 1 to 6 months February 5, 2021

For Acne: “Epiduo was a lifesaver, after trying everything for black spots as well as acne , epiduo was extremely effective. My dermatologist took before and after pictures. At month 3 it was amazing. Epiduo worked so well for me that I don’t even have to go anymore until next January! Make sure you use moisturizer and sunscreen.”

9 / 10
Kaye B. · Taken for 1 to 6 months November 10, 2019

For Acne: “Back in 2016 I had severe acne. It was so painful and it covered my entire face. I tried everything and after a year my face worsened. A friend recommended epiduo and after just a month the acne cleared. I've been using this for years now :) bye bye acne. Note: too much use will cause redness. I'm using it every other day. At night only. And please just use a pea size for the entire face - just a really thin layer.”

10 / 10
Jackie · Taken for 1 to 6 months November 22, 2019

For Acne: “Do not let the negative reviews stir you away from this medication! This acne medication has changed my life. I dealt with severe acne for about two years. I got multiple hydro facials in hope that It would clear my skin but it did not. I began taking epiduo about 4 months ago. The first couple of weeks my skin was dry but that’s about it. At first I felt like it was not working because my acne was still there and I was still having breakouts but I stuck with it. I put it on at night after washing my face. After 4 months my skin has cleared up, I cannot believe that it is this clear. I recommend this product! Stick with it and it will work! Make sure to moisturize and wear sunscreen.”

Taylor August 20, 2019

For Acne: “I was prescribed Epiduo for moderate acne. She unfortunately didn’t discuss how sensitive my skin was, otherwise I probably wouldn’t have been prescribed this. Epiduo is brutal. I thought I could perhaps tolerate the effect it had on my skin in the hope of combatting my acne, but it gradually got worse instead of better. I experienced extreme dryness and cracking. My face felt like it was on fire and it was as if I had a chemical burn. It started to dry out my eyelids, despite completely avoiding the eye area. My lips became chapped and cracked. It hurt to even shower as the water was uncomfortable on my face. I use CeraVe face wash and Cetaphil moisturiser as they are non-comedogenic, but even this made me feel pain. Today I was driven to tears at the extreme pain I was feeling so I’m going to have to stop using it. I appreciate all the success stories and I’m glad that people have experienced positive outcomes with their skin, but the experience for me was absolutely awful.”

3 / 10
Te · Taken for 1 to 6 months November 11, 2019

For Acne: “Was concerned when I first started to use Epiduo because my face started to break out even more. I stayed consistent and by week 3 I started to see really great results. Lots of burning when I first started. Like I would get literally burns around my mouth, eyes, sensitive parts of my face, but after staying consistent and not rubbing so hard when washing my face, the burns stopped”

Li · Taken for 1 to 6 months August 20, 2020

For Acne: “Hi! I’m on my 5th month of using epiduo and it has been a life saver it’s upped my confidence a lot. Recently I’ve gotten a breakout again but that’s expected because of being a teen and all that. But my forehead is so clear and my before and after pictures I can’t even explain.. just incredible work. You have to be patient with this cream and you will see results. Everyone should give it at least a 6 month trial and take before and after pictures. It stings at the start as the cream adjusts but it soon helps and the acne spots disappear quickly!”

8 / 10

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.