Comparing Diclofenac Topical vs Efudex
| Diclofenac topical | Efudex (fluorouracil) |
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| Diclofenac topical | Efudex (fluorouracil) |
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Prescription and OTC
Prescribed for Back Pain, Osteoarthritis, Pain, Keratosis. Diclofenac topical may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Actinic Keratosis, Basal Cell Carcinoma, Skin Cancer, Keratosis. Efudex may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Diclofenac topical | More about Efudex (fluorouracil) | ||||||||
| Ratings & Reviews | |||||||||
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Diclofenac topical has an average rating of 7.0 out of 10 from a total of 466 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 25% reported a negative effect. |
Efudex has an average rating of 7.4 out of 10 from a total of 127 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Diclofenac topical side effects |
View all Efudex side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Diclofenac topical prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Aspercreme Arthritis Pain Relief Gel, Diclozor, Flector Patch, Licart, Pennsaid, Profinac, Solaraze, Voltaren Arthritis Pain Gel, Xrylix View more | Other fluorouracil brands include: Carac, Efudex Occlusion Pack, Fluoroplex, Tolak | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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1.8 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 128 drugs are known to interact with Diclofenac topical:
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A total of 6 drugs are known to interact with Efudex:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||
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October 16, 2000 |
July 29, 1970 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.