Comparing Cyclosporine vs Tacrolimus

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Cyclosporine	Tacrolimus	Enter another drug to compare

Cyclosporine

Tacrolimus

Prescription only

Prescribed for Eczema, Psoriasis, Cogan's Syndrome, Evan's Syndrome, Organ Transplant - Rejection Prophylaxis, Crohn's Disease, Focal Segmental Glomerulosclerosis, Graft Versus Host Disease, Immune... View more

Prescription only

Prescribed for Organ Transplant - Rejection Reversal, Organ Transplant - Rejection Prophylaxis, Nephrotic Syndrome, Graft Versus Host Disease, Crohn's Disease. Tacrolimus may also be used for... View more

More about Cyclosporine

More about Tacrolimus

Ratings & Reviews

Cyclosporine has an average rating of 9.1 out of 10 from a total of 23 ratings on Drugs.com. 91% of reviewers reported a positive effect, while 4% reported a negative effect.

Tacrolimus has an average rating of 7.9 out of 10 from a total of 49 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 12% reported a negative effect.

View all 23 reviews

View all 49 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Cyclosporine side effects

View all Tacrolimus side effects

Drug Class

Calcineurin inhibitors

Calcineurin inhibitors

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	30 each
Strength	modified 25 mg
Per unit^*	$0.73
Cost^*	$21.96

View all Cyclosporine prices

Quantity	100 each
Strength	1 mg
Per unit^*	$1.25 - $1.39
Cost^*	$124.83 - $139.33

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Dosage Forms

Injectable solution
Oral capsule
Oral liquid

Oral capsule

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

5.6 hours

21.2 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 815 drugs are known to interact with Cyclosporine:

163 major drug interactions (553 brand and generic names)
606 moderate drug interactions (2208 brand and generic names)
46 minor drug interactions (186 brand and generic names)

A total of 870 drugs are known to interact with Tacrolimus:

256 major drug interactions (938 brand and generic names)
593 moderate drug interactions (2112 brand and generic names)
21 minor drug interactions (142 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Grapefruit and grapefruit juice can increase the levels of cycloSPORINE in your body and should... View more

Tacrolimus should be taken on a consistent schedule before or after you eat at the same times each... View more

Disease Interactions

First Approval Date

November 14, 1983

April 08, 1994

WADA Class View classifications

N/A

More Information

Patient Resources

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Cyclosporine vs Tacrolimus

See also:

Stelara

Taltz

Skyrizi

Humira

Plaquenil

Enbrel

Remicade

CellCept

Imuran

Arava

Further information

Comparing Cyclosporine vs Tacrolimus

See also:

Further information

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