Comparing Citalopram vs Amitriptyline
Citalopram | Amitriptyline |
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Citalopram | Amitriptyline |
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Prescription only
Citalopram may be used to treat depression and off-label to treat other conditions such as anxiety and OCD. Side effects such as insomnia, drowsiness, dry mouth, nausea, and increased sweating may... View more |
Prescription only
Amitriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. It may be used off-label to treat other conditions such as... View more |
Related suggestions Depression
Anxiety and Stress
Vulvodynia
Persistent Depressive Disorder
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More about Citalopram | More about Amitriptyline | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Citalopram has an average rating of 7.5 out of 10 from a total of 2216 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 15% reported a negative effect. |
Amitriptyline has an average rating of 7.6 out of 10 from a total of 1767 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 16% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: citalopram side effects in more detail. |
See also: amitriptyline side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all citalopram prices |
View all amitriptyline prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Celexa |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
35 hours |
16 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 708 drugs are known to interact with citalopram:
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A total of 705 drugs are known to interact with amitriptyline:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
July 17, 1998 |
April 07, 1961 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.