Comparing Butalbital Compound vs Excedrin

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Butalbital Compound (aspirin / butalbital / caffeine)	Excedrin (acetaminophen / aspirin / caffeine)	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Butalbital Compound (aspirin / butalbital / caffeine)	Excedrin (acetaminophen / aspirin / caffeine)	Enter another drug to compare
Prescription only Prescribed for Migraine, Headache, Pain. Butalbital Compound may also be used for purposes not listed in this medication guide.	Over-the-counter Prescribed for Migraine, Osteoarthritis, Pain/Fever. Excedrin may also be used for purposes not listed in this medication guide.	Related suggestions Migraine Sumatriptan Ubrelvy Nurtec ODT Imitrex Rizatriptan Topiramate
More about (aspirin / butalbital / caffeine)	More about Excedrin (acetaminophen / aspirin / caffeine)
Ratings & Reviews
Butalbital Compound has an average rating of 9.0 out of 10 from a total of 28 ratings on Drugs.com. 86% of reviewers reported a positive effect, while 0% reported a negative effect.	Excedrin has an average rating of 6.8 out of 10 from a total of 39 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 33% reported a negative effect.
View all 28 reviews	View all 39 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
View all Butalbital Compound side effects	View all Excedrin side effects
Drug Class
Analgesic combinations	Analgesic combinations
Generic Availability
Lower cost generic approved	N/A
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
N/A	Oral tablet
Brand Names
Other aspirin / butalbital / caffeine brands include: Farbital, Fiorinal, Fiormor, Fiortal, Fortabs	Other acetaminophen / aspirin / caffeine brands include: Anacin Advanced Headache Formula, Arthriten, Arthriten Inflammatory Pain Formula, Backaid Inflammatory Pain Formula, Bayer Migraine Formula, ConRx Pain Reliever, CVS Extra Strength Headache Relief, Excedrin Extra Strength, Excedrin Migraine, Extra Pain Relief, Genace, Goody's Extra Strength, Goody's Extra-Strength Headache Powders, Goody's Headache Powders, Medique Pain-Off, Migraine Formula, Migraine Relief, PainAid Extra-Strength Formula, Pamprin Max Menstrual Pain Relief, Vanquish View more
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
35 hours	10 hours
CSA Schedule ¹ View glossary of CSA terms
3 Moderate abuse potential Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
C Category C Risk cannot be ruled out See the full pregnancy warnings document.	N Category N Not classified See the full pregnancy warnings document.
Drug Interactions
A total of 896 drugs are known to interact with Butalbital Compound: 98 major drug interactions (379 brand and generic names) 743 moderate drug interactions (3563 brand and generic names) 55 minor drug interactions (224 brand and generic names)	A total of 588 drugs are known to interact with Excedrin: 72 major drug interactions (232 brand and generic names) 442 moderate drug interactions (2069 brand and generic names) 74 minor drug interactions (339 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Ask your doctor before using butalbital together with alcohol, this can add to dizziness... View more	Ask your doctor before using acetaminophen together with alcohol. This can cause serious side... View more
Disease Interactions
Coagulation Acute alcohol intoxication Drug dependence Liver disease Porphyria Rash Respiratory depression Cardiac disease Hypertension Psychiatric disorders PUD Asthma GI toxicity Renal dysfunction Reye's syndrome Adrenal insufficiency Depression Hematologic toxicity Osteomalacia Paradoxical reactions Cardiotoxicity Liver disease Renal dysfunction Seizure disorders GERD Anemia Dialysis G-6-PD deficiency Hepatotoxicity	Alcoholism Liver disease Coagulation Cardiac disease Hypertension Psychiatric disorders PUD Asthma GI toxicity Renal dysfunction Reye's syndrome PKU Cardiotoxicity Liver disease Renal dysfunction Seizure disorders GERD Anemia Dialysis G-6-PD deficiency Hepatotoxicity
First Approval Date
N/A	N/A
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Support group	Side effects Drug interactions Dosage Pregnancy warnings Support group
Patient Resources
N/A	Excedrin uses
Professional Resources
N/A	N/A
Related Treatment Guide
Migraine Headache Pain	Migraine Osteoarthritis Pain/Fever

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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Comparing Butalbital Compound vs Excedrin

See also:

Ubrelvy

Nurtec ODT

Qulipta

Celebrex

Botox

Verapamil

Sumatriptan

Metoclopramide

Celecoxib

Propranolol

Further information

Comparing Butalbital Compound vs Excedrin

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