Comparing Ambien vs Lunesta
| Ambien (zolpidem) | Lunesta (eszopiclone) |
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| Ambien (zolpidem) | Lunesta (eszopiclone) |
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Prescription only
Ambien induces sleep; however, Ambien CR, in particular, may impair physical and mental capabilities the next day. Ambien has also been associated with complex or dangerous sleep-related behaviors... View more |
Prescription only
Prescribed for Insomnia. Lunesta may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Ambien (zolpidem) | More about Lunesta (eszopiclone) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Ambien has an average rating of 7.0 out of 10 from a total of 559 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 21% reported a negative effect. |
Lunesta has an average rating of 5.9 out of 10 from a total of 342 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 35% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Ambien side effects |
View all Lunesta side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Ambien prices |
View all Lunesta prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other zolpidem brands include: Ambien CR, Edluar, Zolpimist |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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2.6 hours |
6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 481 drugs are known to interact with Ambien:
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A total of 385 drugs are known to interact with Lunesta:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 16, 1992 |
December 15, 2004 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.