Comparing Ambien vs Lunesta
| Ambien (zolpidem) | Lunesta (eszopiclone) |
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| Ambien (zolpidem) | Lunesta (eszopiclone) |
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Prescription only
Ambien induces sleep; however, Ambien CR, in particular, may impair physical and mental capabilities the next day. Ambien has also been associated with complex or dangerous sleep-related behaviors... View more |
Prescription only
Prescribed for Insomnia. Lunesta may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Ambien (zolpidem) | More about Lunesta (eszopiclone) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Ambien has an average rating of 7.0 out of 10 from a total of 560 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 21% reported a negative effect. |
Lunesta has an average rating of 5.9 out of 10 from a total of 342 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 35% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Ambien side effects |
View all Lunesta side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Ambien prices |
View all Lunesta prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other zolpidem brands include: Ambien CR, Edluar, Zolpimist |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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2.6 hours |
6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 482 drugs are known to interact with Ambien:
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A total of 385 drugs are known to interact with Lunesta:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 16, 1992 |
December 15, 2004 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.