Amantadine Alternatives Compared
| Amantadine | Carbidopa / levodopa | Sinemet |
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| Amantadine | Carbidopa / levodopa | Sinemet (carbidopa / levodopa) |
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Prescription only
Amantadine may be used to treat dyskinesia or reduce the number of OFF episodes in those with Parkinson's disease (PD) OR in the treatment or prevention of Influenza A viral infection. Nausea... View more |
Prescription only
Carbidopa/levodopa is a medication that may be used for the treatment of Parkinson's disease that is available in three different strengths: carbidopa/levodopa 10/100, carbidopa/levodopa 25/100 and... View more |
Prescription only
Sinemet is a medication that may be used for the treatment of Parkinson's disease that is available in three different strengths: Sinemet 25/100, Sinemet 25/250, and Sinemet 10/100. Dyskinesias... View more |
Related suggestions |
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| More about Amantadine | More about Carbidopa / levodopa | More about Sinemet (carbidopa / levodopa) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Amantadine has an average rating of 6.8 out of 10 from a total of 49 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 24% reported a negative effect. |
Carbidopa / levodopa has an average rating of 7.1 out of 10 from a total of 89 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 22% reported a negative effect. |
Sinemet has an average rating of 7.8 out of 10 from a total of 30 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 11% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: amantadine side effects in more detail. |
See also: carbidopa / levodopa side effects in more detail. |
See also: Sinemet side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all amantadine prices |
View all carbidopa / levodopa prices |
View all Sinemet prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Gocovri, Osmolex ER | Atamet, Dhivy, Duopa, Parcopa, Rytary, Sinemet | Other carbidopa / levodopa brands include: Atamet, Dhivy, Duopa, Parcopa, Rytary | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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19 hours |
2.3 hours |
2.3 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 126 drugs are known to interact with amantadine:
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A total of 473 drugs are known to interact with carbidopa / levodopa:
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A total of 473 drugs are known to interact with Sinemet:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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February 14, 1968 |
May 02, 1975 |
May 02, 1975 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.