Comparing Alka-Seltzer Original vs Pepto-Bismol
| Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate) | Pepto-Bismol (bismuth subsalicylate) |
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| Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate) | Pepto-Bismol (bismuth subsalicylate) |
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Over-the-counter
Prescribed for Gas, Indigestion, Headache. Alka-Seltzer Original may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Prescribed for Helicobacter Pylori Infection, Diarrhea - Chronic, Indigestion, Traveler's Diarrhea, Lymphocytic Colitis, Diarrhea, Diarrhea - Acute. Pepto-Bismol may also be used for purposes not... View more |
Related suggestions Indigestion
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| More about Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate) | More about Pepto-Bismol (bismuth subsalicylate) | |
| Ratings & Reviews | ||
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Alka-Seltzer Original has an average rating of 8.5 out of 10 from a total of 4 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 0% reported a negative effect. |
Pepto-Bismol has an average rating of 7.4 out of 10 from a total of 35 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||
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View all Alka-Seltzer Original side effects |
View all Pepto-Bismol side effects |
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| Drug Class | ||
| Generic Availability | ||
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N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||
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N/A |
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| Brand Names | ||
| Other aspirin/citric acid/sodium bicarbonate brands include: Alka-Seltzer Extra Strength, Alka-Seltzer Lemon-Lime, Bromo Seltzer, Effervescent Pain Relief, Medique Medi-Seltzer, Picot Plus, Vida Mia Pain Relief, Winco Foods Effervescent Antacid and Pain Relief, Zee-Seltzer Antacid and Pain Reliever View more | Other bismuth subsalicylate brands include: Bismarex, Bismatrol, Bismatrol Maximum Strength, Childrens Kaopectate, Kaopectate, Kola-Pectin DS, Maalox Total Relief, Peptic Relief, Pepto-Bismol InstaCool, Pepto-Bismol Original Strength, Percy Medicine, Pink Bismuth, Soothe Caplets, Stomach Relief View more | |
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||
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10 hours |
33 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||
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Category N
Not classified
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Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | ||
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A total of 477 drugs are known to interact with Alka-Seltzer Original:
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A total of 141 drugs are known to interact with Pepto-Bismol:
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| Alcohol/Food/Lifestyle Interactions | ||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||
| First Approval Date | ||
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N/A |
N/A |
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| WADA Class View classifications | ||
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N/A |
N/A |
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| More Information | ||
| Patient Resources | ||
| Professional Resources | ||
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N/A |
N/A |
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| Related Treatment Guide | ||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.