Comparing 5-HTP vs St. John's Wort
| 5-HTP (5-hydroxytryptophan) | St. john's wort |
|
|---|
| 5-HTP (5-hydroxytryptophan) | St. john's wort |
|
|---|---|---|
|
Over-the-counter
Used for ADHD, Anxiety, Insomnia, Headache. 5-HTP may also be used for purposes not listed in this medication guide. |
Over-the-counter
Used for Night Terrors, Depression. St. john's wort may also be used for purposes not listed in this medication guide. |
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| More about 5-HTP (5-hydroxytryptophan) | More about St. john's wort | |
| Ratings & Reviews | ||
|
5-HTP has an average rating of 6.6 out of 10 from a total of 154 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 25% reported a negative effect. |
St. john's wort has an average rating of 7.8 out of 10 from a total of 144 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 15% reported a negative effect. |
|
| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||
View all 5-HTP side effects |
View all St. john's wort side effects |
|
| Drug Class | ||
| Generic Availability | ||
|
N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||
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N/A |
N/A |
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| Brand Names | ||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||
|
4 hours |
N/A |
|
| CSA Schedule 1 View glossary of CSA terms | ||
|
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
|
| Pregnancy Category | ||
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Category N
Not classified
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Category N
Not classified
|
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| Drug Interactions | ||
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A total of 100 drugs are known to interact with 5-HTP:
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A total of 635 drugs are known to interact with St. john's wort:
|
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| Alcohol/Food/Lifestyle Interactions | ||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||
|
N/A |
N/A |
|
| WADA Class View classifications | ||
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N/A |
N/A |
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| More Information | ||
| Patient Resources | ||
| Professional Resources | ||
| Related Treatment Guide | ||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.