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5-HTP Side Effects

Generic Name: 5-hydroxytryptophan

Note: This page contains information about the side effects of 5-hydroxytryptophan. Some of the dosage forms included on this document may not apply to the brand name 5-HTP.

Applies to 5-hydroxytryptophan: oral capsule

Get emergency medical help if you have any of these signs of an allergic reaction while taking 5-hydroxytryptophan (the active ingredient contained in 5-HTP) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although not all side effects are known, 5-hydroxytryptophan is thought to be possibly safe when taken for a short period of time.

Stop using 5-hydroxytryptophan and call your doctor at once if you have:

  • severe tingling or numbness;

  • skin rash, bruising, fever; or

  • muscle pain or weakness.

Common side effects may include:

  • drowsiness;

  • nausea, vomiting, stomach pain, heartburn;

  • diarrhea; or

  • loss of interest in sex.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Not all side effects for 5-HTP may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

More about 5-HTP (5-hydroxytryptophan)

Consumer resources

Professional resources

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